A connection between matrix orthogonal polynomials and non-abelian integrable lattices is investigated in this paper. The normalization factors of matrix orthogonal polynomials expressed by quasi-determinant are shown to be solutions of non-abelian Toda lattice in semidiscrete and full-discrete cases. Moreover, with a moment modification method, we demonstrate that the Bäcklund transformation of non-abelian Toda given by Popowicz is equivalent to the non-abelian Volterra lattice, whose solutions could be expressed by quasi-determinants as well.