Ability of SARC-F to Find Probable Sarcopenia Cases in Older Adults

Sacar, Duygu Erbas; Kılıç, Cihan; Karan, Mehmet Akif; Bahat, Gülistan

doi:10.1007/s12603-021-1617-3

Cited by 30 publications

(33 citation statements)

References 23 publications

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“…On the other hand, SARC-F has been reported having low sensitivity (4-35%) but high specificity (80-98%) [3,4]. We have recently analyzed the sensitivity of SARC-F by applying different thresholds [5]. In this study, we used the area under the receiver-operating characteristic (ROC) curve to test the predictive accuracy to determine a suitable cut-off point in this analysis.…”

Section: To the Editormentioning

confidence: 99%

“…For a given test, a low sensitivity score indicates a lesser capacity of a screening tool to detect individuals having the condition of interest. Our recent report put forward the SARC-F score ≥ 1 is better for screening, while the commonly used cut point ≥ 4 is better for excluding probable sarcopenia [5]. It would be welcome if the authors could have an additional analysis by the ≥ 1 and 2 cut points.…”

Section: To the Editormentioning

confidence: 99%

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SARC-F can detect sarcopenia with a high sensitivity

Bahat

Sacar

2021

Aging Clin Exp Res

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Section: To the Editormentioning

confidence: 99%

Section: To the Editormentioning

confidence: 99%

SARC-F can detect sarcopenia with a high sensitivity

Bahat

Sacar

2021

Aging Clin Exp Res

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“…Observably, the cut-off score that the performer uses to define a positive result will alter the prevalence of positive screening outcomes and thereby, the sensitivity and specificity of a given test. We have recently analyzed the sensitivity of SARC-F by applying different thresholds within this context [20]. A cut-off point >=1 increased sensitivity to 84.2% with accompanying acceptable specificity of 40.5%.…”

Section: Sarc-f: Sensitivity and Specificity To Diagnose Sarcopeniamentioning

confidence: 99%

“…We showed that a SARC-F cut-off point >=2 demonstrated the best synthesis of sensitivity (64.9%) and specificity (67.9%) for detecting probable sarcopenia. Hence, a SARC-F score of >= 1 has been suggested better for screening and a cutoff point of >= 4 better for excluding probable sarcopenia [20]. Very recently, Dodds et al also suggested that a SARC-F cut-off point of one or above improved sensitivity (65%) with a 72% specificity [21].…”

Section: Sarc-f: Sensitivity and Specificity To Diagnose Sarcopeniamentioning

confidence: 99%

SARC-F test in Sarcopenia and Frailty: A Narrative Review

Bahat¹

2021

JNFP

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SARC-F is a commonly used screening tool for sarcopenia case finding due to its user-friendly and very practical application. It has been introduced to screen for sarcopenia with simple functional questions obviating the need for the measurement of muscle mass. A score equal to or greater than 4 has been reported as predictive of poor outcomes. Sarcopenia is a geriatric syndrome associated with well-known adverse consequences. The growing awareness of sarcopenia as a determinant of poor health in older people has underlined the importance of rapidly diagnosing sarcopenia, which will aid clinicians for implementing prevention and treatment strategies. It has been recommended formal tool for sarcopenia screening/case-finding. In this narrative review, we aimed to evaluate the use of SARC-F, its ability to screen and diagnose sarcopenia and its potential use in the fields other than sarcopenia, i.e. frailty. We conclude that SARC-F stands as one of the most useful and applied tool in studies focusing on screening and diagnosis of sarcopenia. In addition, it has a great potential to be used as a frailty screening tool.

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“…Since SARC-F has low sensitivity, but high specificity [ 11 , 14 ], the risk of sarcopenia assessed by SARC-F may be underestimated [ 11 , 14 , 15 , 16 ]. Another cut-off score was recently reported for predicting the risk of sarcopenia (SARC-F = 1) [ 17 ] and the usefulness of SARC-F for detecting the risk of frailty or falls has been demonstrated [ 18 , 19 ]. A previous study revealed a relationship between SARC-F scores and muscle mass [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Relationships between Pre-Stroke SARC-F Scores, Disability, and Risk of Malnutrition and Functional Outcomes after Stroke—A Prospective Cohort Study

et al. 2021

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SARC-F is a screening tool for sarcopenia; however, it has not yet been established whether SARC-F scores predict functional outcomes. Therefore, we herein investigated the relationship between SARC-F scores and functional outcomes in stroke patients. The primary outcome in the present study was the modified Rankin Scale (mRS) 3 months after stroke. The relationship between SARC-F scores and poor functional outcomes was examined using a logistic regression analysis. Furthermore, the applicability of SARC-F scores to the assessment of poor functional outcomes was analyzed based on the area under the receiver operating curve (ROC). Eighty-one out of the 324 patients enrolled in the present study (25%) had poor functional outcomes (mRS ≥ 4). The results of the multivariate analysis revealed a correlation between SARC-F scores (OR = 1.29, 95% CI = 1.05–1.59, p = 0.02) and poor functional outcomes. A cut-off SARC-F score ≥ 4 had low-to-moderate sensitivity (47.4%) and high specificity (87.3%). The present results suggest that the measurement of pre-stroke SARC-F scores is useful for predicting the outcomes of stroke patients.

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Ability of SARC-F to Find Probable Sarcopenia Cases in Older Adults

Cited by 30 publications

References 23 publications

SARC-F can detect sarcopenia with a high sensitivity

SARC-F can detect sarcopenia with a high sensitivity

SARC-F test in Sarcopenia and Frailty: A Narrative Review

Relationships between Pre-Stroke SARC-F Scores, Disability, and Risk of Malnutrition and Functional Outcomes after Stroke—A Prospective Cohort Study

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