Ablation therapy in atrial fibrillation

Bhatti, Alysha; Oakeshott, Pippa; Dhinoja, Mehul; Grapsa, Julia

doi:10.1136/bmj.l6428

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…This procedure is contraindicated in patients who cannot be anti-coagulated one month before and at least several months after the procedure. Atrio-ventricular nodal ablation with pacemaker implantation may be beneficial for older patients with tachycardia induced cardiomyopathy and persons with refractory ventricular rate control despite maximal medical treatment [61].…”

Section: Converting the Rhythm Backmentioning

confidence: 99%

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Leowattana¹

2020

BJSTR

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The health benefits of regular moderate-intensity exercise are indisputable. Recently, concerns have been raised about atrial fibrillation (AF) risk of strenuous endurance exercise. On the other hand, most modest exercise intensity is associated with a decreased risk of AF. Many investigators indicated a J-shaped or U-shaped relationship between the broad range of physical activity and AF. The mechanism underlying the increased risk of AF with endurance exercise may be different from the pathophysiology of a reduced risk of moderate exercise. It was speculated that long-term endurance exercise may promote cardiac structural changes (dilatation and fibrosis), increase vagal tone, bradycardia, and inducing AF. It can cause serious symptoms that disturb the intensity of exercise activity and hence more attention should be considered to prevent AF during endurance exercise. Moreover, the reduction of exercise intensity will be the most effective prevention strategy to decrease AF risk.

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Section: Converting the Rhythm Backmentioning

confidence: 99%

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Leowattana¹

2020

BJSTR

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“…Ablation therapy (catheter ablation) is an alternative option, especially for AF patients who do not tolerate anti-arrhythmic agents (Bhatti et al, 2019), and in terms of therapeutic effect, it seems to be more effective than anti-arrhythmic agents as well (Hakalahti et al, 2015). The principle of catheter ablation therapy is creating lesions with a catheter using radiofrequency energy or cryoenergy.…”

Section: Introductionmentioning

confidence: 99%

Current progress of computational modeling for guiding clinical atrial fibrillation ablation

Liu

Tong

et al. 2021

J. Zhejiang Univ. Sci. B

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Atrial fibrillation (AF) is one of the most common arrhythmias, associated with high morbidity, mortality, and healthcare costs, and it places a significant burden on both individuals and society. Anti-arrhythmic drugs are the most commonly used strategy for treating AF. However, drug therapy faces challenges because of its limited efficacy and potential side effects. Catheter ablation is widely used as an alternative treatment for AF. Nevertheless, because the mechanism of AF is not fully understood, the recurrence rate after ablation remains high. In addition, the outcomes of ablation can vary significantly between medical institutions and patients, especially for persistent AF. Therefore, the issue of which ablation strategy is optimal is still far from settled. Computational modeling has the advantages of repeatable operation, low cost, freedom from risk, and complete control, and is a useful tool for not only predicting the results of different ablation strategies on the same model but also finding optimal personalized ablation targets for clinical reference and even guidance. This review summarizes three-dimensional computational modeling simulations of catheter ablation for AF, from the early-stage attempts such as Maze III or circumferential pulmonary vein isolation to the latest advances based on personalized substrate-guided ablation. Finally, we summarize current developments and challenges and provide our perspectives and suggestions for future directions.

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“…Despite its benefits, radiofrequency ablation is still an invasive and expensive procedure, and the recurrence rate occurs is up to 50% in 1 year. (Bhatti, Oakeshott, Dhinoja, & Grapsa, 2019) The ability to predict postablation recurrence would have implications on patient outcomes and healthcare cost at meantime.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of Morphology‐Voltage‐P‐wave duration (MVP) score as a predictor of atrial fibrillation recurrence after pulmonary vein isolation

Yang

Ning

Cong

et al. 2020

Noninvasive Electrocardiol

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Ablation therapy in atrial fibrillation

Cited by 5 publications

References 18 publications

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Current progress of computational modeling for guiding clinical atrial fibrillation ablation

Usefulness of Morphology‐Voltage‐P‐wave duration (MVP) score as a predictor of atrial fibrillation recurrence after pulmonary vein isolation

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Ablation therapy in atrial fibrillation

Cited by 5 publications

References 18 publications

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Endurance Exercise Induced Atrial Fibrillation (AF): Pathophysiology, Treatment and Prevention

Current progress of computational modeling for guiding clinical atrial fibrillation ablation

Usefulness of Morphology‐Voltage‐P‐wave duration (MVP) score as a predictor of atrial fibrillation recurrence after pulmonary vein isolation

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Product

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Usefulness of Morphology‐Voltage‐P‐wave duration (MVP) score as a predictor of atrial fibrillation recurrence after pulmonary vein isolation