Abnormal Atrioventricular Node Conduction and Atrioventricular Nodal Reentrant Tachycardia in Patients Older Versus Younger Than 65 Years of Age

Grecu, Mihaela; Floria, Mariana; Georgescu, Cătălina Arsenescu

doi:10.1111/j.1540-8159.2008.02261.x

Cited by 11 publications

(8 citation statements)

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“…An increase in the length of inferior AVN extensions with fibrotic changes in the transitional zone might contribute to a longer AVNERP, dual, or multiple AVN conduction patterns, and the development of AVN re-entry. 18 The morphology of the AV node changes with aging, and becomes larger with a right inferior extension from 1 year of age until 20. 19 Age-related fibrofatty tissue could cause the transitional cells to separate and result in changes in the sequence of fast and slow inputs.…”

Section: Paradoxical Changes In Av Nodal Electrophysiological Charactmentioning

confidence: 99%

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Tseng

Tsai

et al. 2011

Circ J

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Background: This study aimed to investigate the impact of aging on electrophysiological characteristics in patients with atrioventricular nodal re-entrant tachycardia (AVNRT). Methods and Results:The 2,111 patients who underwent an electrophysiological study and radiofrequency (RF) catheter ablation of AVNRT were enrolled. The patients were divided into 4 groups according to age (group 1: <20 years; group 2: 20-39 years; group 3: 40-59 years; and group 4: ≥60 years). The gender distribution differed with age. The atrio-Hisian interval, and effective refractory periods (ERP) of the right atrium, ventricle, antegrade slow pathway, retrograde slow pathway and fast pathway, and tachycardia cycle length all increased with age. However, a paradoxical change in the fast pathway ERP was noted. The fast pathway ERP was significantly longer in group 2 than in other groups, and was associated with the largest tachycardia window. The response to catecholamines was similar between different age groups. Procedure time, radiation time, and complications did not differ. However, the number of RF impulses was higher in group 2 compared with other groups (7.6±9.3, P=0.04), which might imply a differing complexity during the ablation. Conclusions:Paradoxical aging changes of AVN electrophysiological characteristics were associated with a different atrioventricular nodal conduction property and the number of RF impulses. (Circ J 2011; 75: 1581 -1584

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Section: Paradoxical Changes In Av Nodal Electrophysiological Charactmentioning

confidence: 99%

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Tseng

Tsai

et al. 2011

Circ J

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“…Unlike malignant non-transformed cells that secrete angiogenic factors as a result of a hypoxic stimulus or cellular damage, it has been experimentally demonstrated (in vitro), in 1995, that the tumor cells secretes, besides any stimulus, a strong complex of angiogenic factors called TAFC [10]. Numerous groups of researchers have since studied this complex, in order to isolate and identificate it.…”

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confidence: 99%

Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis

Hînganu¹,

Hînganu²,

Bulimar³

et al. 2018

Rev. Chim.

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Establishing the treatment strategy for patients diagnosed with colorectal cancer is based on their imaging and immunohistochemical evaluation. Depending on the stage of tumor invasion and its aggressiveness, is individualized, surgical, oncological, or both treatment. The most important factor for establishing these protocols is the impact of the tumor on intra- and perilesional colorectal vasculature and implicitly on the process of vascular neoformation in the paraneoplastic syndrome. In this regard, we studied a group of patients, colonoscopically diagnosed with colorectal cancer. The study method was to compare the expression of CD34 tumor marker with EMVI (extramural vascular invasion) staging criteria. The results of our study were compared with the intraoperative aspects. In all cases studied tumor extension reached to at least intestinal muscle layer. We conclude that expression of the CD34 marker has always been increased in correlation with EMVI 3-4 stages. In 2 patients with EMVI score 2, the immunohistochemical marker expression was 6% above the maximum threshold. The expression of vascular endothelial proliferation marker is closely correlated with the EMVI score - these values increase proportionally. The use of both criteria for establishing neovasculogenesis, significantly increases the predictability of postoperative progression and long-term survival.

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“…29 It was indicated in the literature that TCL tends to be higher in elderly patients with AVNRT. 24,25,29, 30 Additionally, the AH interval and effective refractory periods of antegrade slow unpaired t-test, respectively.…”

Section: Discussionmentioning

confidence: 98%

Clinical and Electrophysiological Characteristics of Typical Atrioventricular Nodal Reentrant Tachycardia in the Elderly　– Changing of Slow Pathway Location With Aging –

Alihanoğlu

Yıldız

Kılıç

et al. 2015

Circ J

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Abnormal Atrioventricular Node Conduction and Atrioventricular Nodal Reentrant Tachycardia in Patients Older Versus Younger Than 65 Years of Age

Abstract: In patients undergoing RFCA for AVNRT at >65 years of age had a shorter history of tachycardia-related symptoms than patients with lone AVNRT. The longer AVN conduction intervals and refractory period might explain the late development of AVNRT in group 1.

Cited by 11 publications

References 11 publications

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis

Clinical and Electrophysiological Characteristics of Typical Atrioventricular Nodal Reentrant Tachycardia in the Elderly　– Changing of Slow Pathway Location With Aging –

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Abnormal Atrioventricular Node Conduction and Atrioventricular Nodal Reentrant Tachycardia in Patients Older Versus Younger Than 65 Years of Age

Abstract: In patients undergoing RFCA for AVNRT at >65 years of age had a shorter history of tachycardia-related symptoms than patients with lone AVNRT. The longer AVN conduction intervals and refractory period might explain the late development of AVNRT in group 1.

Cited by 11 publications

References 11 publications

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Paradoxical Aging Changes of the Atrioventricular Nodal Properties in Patients With Atrioventricular Nodal Re-Entrant Tachycardia

Correlation Criteria Between Extramural Invasion of Blood Vessels and Immunohistochemical Markers in the Processes of Neovasculogenesis

Clinical and Electrophysiological Characteristics of Typical Atrioventricular Nodal Reentrant Tachycardia in the Elderly – Changing of Slow Pathway Location With Aging –

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Clinical and Electrophysiological Characteristics of Typical Atrioventricular Nodal Reentrant Tachycardia in the Elderly　– Changing of Slow Pathway Location With Aging –