Abnormal pancreatic imaging in Crohn?s disease: prevalence and clinical features

Abstract

It is suggested that abnormal pancreatic imaging is not serious a complication of Crohn's disease, and is unrelated to the course of Crohn's disease.

Prevalence and Clinicopathological Features of Autoimmune Pancreatitis in Japanese Patients With Inflammatory Bowel Disease

“…10 In the present study, the frequency of AIP in CD patients was 0.4% and that of CD in definite AIP patients was 6.5% (2/31; unpublished data). 7,10,23,25-30 The prevalence (0.8%) of AIP in CD patients has seldom been reported.…”

“…3 Type 2 AIP is characterized by a distinct pathology called idiopathic duct-centric pancreatitis (IDCP) 4 or AIP with granulocyte epithelial lesion (GEL). 10 We have retrospectively maintained a database of 7 patients with AIP and IBD in our institution. 6-9 However, far less is known about the clinical spectrum of AIP in Japanese patients with IBD.…”

A new largeCFTRrearrangement illustrates the importance of searching for complex alleles

“…Patient #7, deceased at 37 y, had no children but had never been investigated for infertility. He had severe Crohn's disease and, though recurrent acute pancreatitis has been described in the course of this disease (Weber et al, 1993;Levine and Lukawski-Trubish, 1995;Oishi et al, 2004), the chronic pancreatitis in this patient may, in part at least, have been caused by alcoholism. 22; 23; 10-9; 7; 17 The recommendations for mutation nomenclature (www.hgvs.org/mutnomen/) were used to name CFTR gene sequence variations at the protein level.…”

The NOD2 3020insC Mutation and The Risk of Familial Pancreatic Cancer?

“…It has been suggested that pancreatitis could be an extrahepatic manifestation of inflammatory bowel disease, since its incidence in this disease is greater than that in the general population and in many cases no aetiological factor has been found [ 5 ]. It has been recently identified in Japan that over 6% of Crohn's disease patients had morphological abnormalities of the pancreas [ 6 ]. There is also a notion that Crohn's-associated pancreatitis could be a premalignant state for cystadenocarcinoma of the pancreas [ 7 ].…”