Abnormal paranasal sinuses in patients with cystic fibrosis of the pancreas

Abstract

Radiographic examinations of the paranasal sinuses and chests of 187 patients with C.F. from five months to 27 years of age were reviewed. One hundred eight-five patients consistently had opaque maxillary and ethmoidal sinuses. Forty-five patients had normal chest radiographs. These observations show that the paranasal sinuses are almost always affected in children with C.F. Although opaque paranasal sinuses do not indicate the diagnosis of C.F., clear paranasal sinuses exclude this disease with reasonable certainty.

Sinonasal alterations in computed tomography scans in cystic fibrosis: a literature review of observational studies

“…Since the first reports by Fanconi et al., Andersen, and Farber, the knowledge of CF has advanced significantly . In 1980, Ledesma‐Medina et al . observed that the paranasal sinuses were almost always affected in children with CF.…”

Upper and lower airways associations in patients with chronic rhinosinusitis and bronchiectasis

“…More recently, a comprehensive review of AR and CRS and their subsequent association with the lower airways was published, again demonstrating evidence to support an interdependent airway theory . Certain conditions have long been known to predispose patients to the development of both bronchiectasis and CRS, including CF, PCD, Young's syndrome, and immunodeficiency syndromes . Interestingly, however, a recent study by King et al .…”

Bacteriologia do aspirado do meato médio em pacientes com fibrose cística

“…19 Although paranasal sinus radiological abnormalities are present in nearly all of the cystic fibrosis patients, few of them present with relevant symptoms. 20 Paranasal sinus opacification on plain radiograms is probably secondary to mucosal membrane thickening and mucosal gland dysfunction that leads to an increased production of mucus. 13 Radiography is a poor method for the differential diagnosis of sinus disease, but is sensitive in detecting decreased paranasal cavity transparency; this finding does not always mean a progressive pathological process.…”