Abnormal Respiratory Pattern Generation during Sleep in Patients with Autonomic Dysfunction

McNicholas, Walter T.; Rutherford, R; Grossman, R F; Moldofsky, Harvey; Zamel, Noé; Phillipson, Eliot A.

doi:10.1164/arrd.1983.128.3.429

Cited by 91 publications

(40 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, we did not find an association with the severity of the disease. Other studies could not find any evidence either of significantly increased hypoventilation or sleep apneas in patients with idiopathic PD compared with normal controls, making it unlikely to be disease-dependent in our study [6,26]. Patients with a rigor/akinetic type of PD reported more nightmares in which they injured somebody else.…”

Section: Discussionmentioning

confidence: 55%

The Association between Disease Severity and Sleep-Related Problems in Patients with Parkinson’s Disease

Happe

Lüdemann²,

Berger

2002

Neuropsychobiology

View full text Add to dashboard Cite

Although sleep-related problems are a frequent finding in patients with Parkinson’s disease (PD), the aetiology is still unknown. We examined the associations between disease severity, sleep-related problems and social status in 116 PD patients participating in the FAQT Study, a prospective, German cohort study evaluating determinants of quality of life in PD patients. 47.4% of the patients reported sleep onset difficulties, 26.7% sleep interruptions, 14.7% had five or more sleep-related events during the night and 71.6% showed symptoms of increased daytime somnolence. The disease severity was significantly associated with sleep-related events (p = 0.01), the depression score with sleep onset difficulties (p = 0.04), sleep interruptions (p = 0.01) and the levodopa dose (p < 0.01). We conclude that depressive symptoms and increasing levodopa doses in PD patients mainly cause sleep onset difficulties and sleep interruptions, while the severity of motor symptoms contributes to sleep-related events like sleep walking, heavy sweating and nightmares.

show abstract

Section: Discussionmentioning

confidence: 55%

The Association between Disease Severity and Sleep-Related Problems in Patients with Parkinson’s Disease

Happe

Lüdemann²,

Berger

2002

Neuropsychobiology

View full text Add to dashboard Cite

show abstract

“…Respiration during sleep in idiopathic PD patients has been hitherto poorly investigated and never in a large number of patients [4,13]. There have been some case reports of hypoventilation in patients with posten-cephalitic [14,15] and familial parkinsonism [ 16], but sleep findings were not mentioned.…”

Section: Introductionmentioning

confidence: 99%

Respiration and Heart Rate Variability during Sleep in Untreated Parkinson Patients

Ferini‐Strambi¹,

Franceschi²,

Pinto³

et al. 1992

Gerontology

View full text Add to dashboard Cite

Twenty-six patients with untreated mild to moderate Parkinson’s disease (PD) lasting 5 years or less, were investigated in the sleep laboratory. Sleep architecture and respiration during sleep did not significantly differ from age-matched controls. PD patients showed defective cardiac autonomic control during sleep, mainly parasympathetic but also sympathetic in nature, although they had normal results in conventional autonomic tests during wakefulness. Therefore, autonomic cardiac involvement seems to be an early sign of PD.

show abstract

“…Some neurological dis eases have been related to nocturnal hypoxemia because of central or mixed apncic episodes. Until today, this dis order has been described in Shy-Drager syndrome, famil ial disautonomia [2], cervical cordotomy [3], encephalitis [4] and brainstem infarct [5],…”

Section: Discussionmentioning

confidence: 99%

“…The identification of such phenomena as sleep apnea syndrome is incorrect, since it may also be due to other diseases that produce pathological nocturnal hypoventilation [1], On the other hand, some neurological disorders have been related to night hypoxemia [2][3][4][5], which is produced by changes of the regulator system of respiration that are not well known [4], Therefore, we consider of interest the presentation of a case of nocturnal arterial oxygen desaturation that returned to normal after a sphenoidal meningioma resec tion.…”

Section: Introductionmentioning

confidence: 99%

Nocturnal Arterial Oxygen Desaturation Secondary to a Sphenoidal Meningioma

García‐Río¹,

Prados²,

Racionero³

et al. 1997

Respiration

View full text Add to dashboard Cite

We report the case of a nonobese and nonsmoking 51-year-old man with nocturnal arterial oxygen desaturation that returned to normal after sphenoidal meningioma resection. He presented an important daytime hypersomnia and episodes of nocturnal apnea, without snoring. His arterial blood gases, mechanical properties of the respiratory system, pulmonary diffusing capacity and chemosensitivity were normal. The most frequent causes of nocturnal hypoxemia are examined.

show abstract

Abnormal Respiratory Pattern Generation during Sleep in Patients with Autonomic Dysfunction

Cited by 91 publications

References 19 publications

The Association between Disease Severity and Sleep-Related Problems in Patients with Parkinson’s Disease

The Association between Disease Severity and Sleep-Related Problems in Patients with Parkinson’s Disease

Respiration and Heart Rate Variability during Sleep in Untreated Parkinson Patients

Nocturnal Arterial Oxygen Desaturation Secondary to a Sphenoidal Meningioma

Contact Info

Product

Resources

About