Abnormal troponin I levels after supraventricular tachycardia

Acute coronary syndromes comprise a large spectrum of clinical conditions ranging from unstable angina pectoris to acute ST-elevation myocardial infarction. Chest pain is usually the major symptom of atherosclerotic heart disease; however, it may be challenging to diagnose correctly, especially in the emergency department, because of the ambiguous way that pain is characterized by some patients. Cardiac troponins are sensitive and specific biomarkers used in the diagnosis of myocardial infarction that are released into the bloodstream when cardiac myocytes are damaged by acute ischemia or any other mechanism. They are the cornerstone for the diagnosis, risk assessment, prognosis, and determination of antithrombotic and revascularization strategies. However, troponin elevation indicates the presence, not the mechanism, of myocardial injury. There are many clinical conditions other than myocardial infarction that cause troponin elevation; thus, the physician should be aware of the wide spectrum of disease states that may result in troponin elevation and have a clear understanding of the related pathophysiology to effectively make a differential diagnosis. This review focuses on causes of troponin elevation other than acute coronary syndromes.

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“…Temporal myocyte damage due to hemodynamic compromise is the mechanism responsible for this phenomenon 74,75…”

Section: Cardiac Causes Of Troponin Elevation Other Than Acute Coronamentioning

confidence: 99%

Troponin elevation in conditions other than acute coronary syndromes

Tanındı

Cemri²

2011

VHRM

122

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“…It has been reported that a high ferritin concentration is related to high troponin levels in hemodialysis patients receiving more intravenous iron sucrose [4]. Abnormal troponin I levels have also been reported without acute coronary syndrome [5,6]. We present a case of abnormal troponin I levels in a thalassemia major patient with high ferritin concentration, permanent atrial fibrillation and without acute coronary syndrome.…”

Section: Case Reportmentioning

confidence: 82%

Abnormal troponin I levels in a thalassemia major patient with high ferritin concentration, permanent atrial fibrillation and without acute coronary syndrome

Patanè

Marte

2010

International Journal of Cardiology

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“…The changes in myocyte membrane permeability resulting from the injury could be enough for the release of cardiac troponins from the free cytosolic pool of myocytes without structural damage [39]. Abnormal troponin-I levels after supraventricular tachycardia have been also reported [40]. We present a case of changing axis deviation in a 49-year-old Italian man with atrial fibrillation, exogenous subclinical hyperthyroidism and troponin-I positive without acute coronary syndrome.…”

Section: Case Reportmentioning

confidence: 86%