Abnormalities of the septum pellucidum in schizophrenia

Jp, Luauté; Sanabria, E; Jp, Bauge; Rodde, B

doi:10.1176/jnp.2.4.461

JNP

1990

DOI: 10.1176/jnp.2.4.461

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Abnormalities of the septum pellucidum in schizophrenia

Luauté Jp¹,

E Sanabria²,

Bauge Jp³

et al.

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1993

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Midline cerebral malformations and schizophrenia

Tr²,

George³

et al. 1993

JNP

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To investigate a possible association of midline cerebral malformations with psychotic disorders, MRI and CT scans were blindly evaluated for 52 patients with schizophrenia, 9 with schizoaffective disease, and 79 consecutive nonpsychotic control subjects. Midline abnormalities were present in 10 of 61 patients (16.4%) versus 4 of 79 control subjects (5.1%; P < 0.05, chi-square). Of 52 schizophrenic patients, 8 had abnormalities of the septum pellucidum (SP): 5 had cavum vergae (CaV), 2 had cavum septum pellucidum (CaSP), and 1 had agenesis of the corpus callosum and SP. Of 9 schizoaffective patients, 2 had SP abnormalities: 1 CaV and 1 CaSP. Abnormalities of the SP, especially CaV, were significantly more frequent in women than in men (P < 0.02, chi-square).

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Midline cerebral malformations and schizophrenia

Tr²,

George³

et al. 1993

JNP

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Abnormalities of the septum pellucidum in schizophrenia

Cited by 1 publication

References 2 publications

Midline cerebral malformations and schizophrenia

Midline cerebral malformations and schizophrenia

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