ABO Blood Groups and Their Relationship with Coagulation Factor VIII in Healthy Adults

Azad, Afrina Binte; Akhter, Qazi Shamima; Islam, Mohammad Aminul; Mukta, Farzana Yeasmin; Afroz, Lily; Layla, Khushbun Nahar; Akter, Tahmina; Islam, Shamanta; Adnan, Amro

doi:10.4236/jbm.2021.99005

Cited by 1 publication

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Te fndings of this study also mirrored the fndings of Azad et al [13] who observed no signifcant diference on blood groups AB, A, and B concerning coagulation FVIII.…”

Section: Discussionsupporting

confidence: 88%

Association between Blood Group and Change in Coagulation Factors in Plasma Preparations for Transfusion Purpose at Kisii Teaching and Referral Hospital

Ogolla,

Nyanchongi,

Demba

2023

Advances in Hematology

View full text Add to dashboard Cite

Background. Blood component therapy helps in managing patients with reduced hematopoiesis, elevated peripheral destruction of cells, and generalized blood loss (bleeding). Increased prevalence of arterial and venous thrombotic disease linked to the impact of ABO blood group on plasma levels of coagulation glycoprotein is demonstrated by blood group non-O persons. Objective. This study had a main objective of determining the association between blood group and change in coagulation factors in plasma preparation for transfusion purpose. Methods. The study employed a longitudinal study design. Factor assay evaluation was done by the use of Erba Mannheim ECL 105 semiautomated coagulation analyzer from India. Thawing meant for consequent coagulation factor analysis and sequential testing of stored cryoprecipitate and fresh frozen plasma was performed by the use of Stericox plasma thawing bath before being analyzed by the coagulation analyzer. Blood group of the collected blood sample in purple EDTA vacutainer was analyzed using blood antisera and a clean white tile, and results were recorded which helped in establishing the association existing between plasma and blood group. The data were fed into Excel and were evaluated by the use of SPSS version 25. Results. There was no significant association between coagulation factors in fresh frozen plasma and blood group, coagulation factors in cryoprecipitate plasma and blood group of the donors showed that the relationship was not significant with, (r = −0.116, −0.097, 0.007 and 0.047 with p value (0.900, 0.087, 0.096 and 0.096), respectively, which are greater than 0.005 standard alpha value. Conclusion. This study has shown no significant association existing between blood group and change in coagulation factors in plasma preparations at Kisii Teaching and Referral Hospital.

show abstract

“…Te fndings of this study also mirrored the fndings of Azad et al [13] who observed no signifcant diference on blood groups AB, A, and B concerning coagulation FVIII.…”

Section: Discussionsupporting

confidence: 88%