Abortus bei Leptospirosis canicola

Focal Bacterial Infections

“…Pathologic changes in the liver, which may be found in 95% of infants dying with congenital syphilis [57], include diffuse hepatitis or focal areas of inflammation, both frequently accompanied by increased connective tissue and enlargement of the liver [15,[57][58][59]. Involvement of liver has also been documented, on the basis of isolation of organisms or their identification in histologic sections, in newborns with intrauterine infection caused by various Leptospira species (Leptospira icterohaemorrhagiae [60,61], Leptospira pomona [62], Leptospira canicola [63], Leptospira kasman [64]).…”

“…In three large series, including almost 500 infants who died after placement of umbilical vein catheters, 29 infants were found to have purulent infections of hepatic vessels or parenchyma [37,75,77]. Use of venous catheters for infusion of hypertonic or acidic solutions may provide a necrotic focus for abscess formation [21,32,[34][35][36]76,77], and prolonged [5,22,32,77] or repeated [63] catheterization of a necrotic umbilical stump provides an ideal pathway for introduction of pathogenic organisms. It has been postulated that some hepatic abscesses have been caused by infusion of contaminated plasma [28] or by the use of nonsterile umbilical catheters [75].…”