In this paper, we consider Bianchi type III and Kantowski-Sachs spacetimes and discuss the behavior of time-varying constants G and Λ by using two symmetric techniques, namely, kinematic self-similarity and matter collineation. In the kinematic self-similarity technique, we investigate the behavior of the first and the second kinds. In the matter collineation technique, we consider usual, modified, and completely modified matter collineation equations while studying the behavior of these constants. Further, we reduce the results for dust, radiation, and stiff fluids. We find that Λ is a decreasing time function while G is an increasing time function. This corresponds to the earlier results available in the literature for other spacetimes. Further, we find that the deceleration parameter attains a negative value, which shows that the expansion of the universe is accelerating.