About the causes and therapy of depressive disorders in COVID-19

Abritalin, E.

doi:10.17116/jnevro202112108187

Cited by 8 publications

(3 citation statements)

References 16 publications

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“…The direct viral invasion of the CNS is infrequent, even among patients experiencing severe symptoms. Additionally, the development or exacerbation of mental disorders can be facilitated by SARS-CoV-2-induced coagulopathy [88,89].…”

Section: Mental Disordersmentioning

confidence: 99%

“…Mental disorders can manifest during the acute phase of COVID-19 or following the alleviation of its primary symptoms. Furthermore, COVID-19 can trigger the exacerbation of pre-existing psychiatric pathology [89]. Experts in mental disorders have concluded that within the first year of the pandemic, there was a surge of 27.6% in severe depressive disorders worldwide, while anxiety disorders increased by 25.6% [84].…”

Section: Mental Disordersmentioning

confidence: 99%

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Factors affecting the severity of COVID-19 and the development of complications

Radygina,

Mochalova

2023

Microbiology Independent Research Journal (MIR Journal)

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Due to the prevalence and diversity of both symptoms and outcomes of COVID-19, understanding the factors that determine the risk of the severe course of this disease and its possible complications is of particular importance. In this review, we present the information on the specifics of COVID-19 pathogenesis and give a theoretical justification for the factors that determine the course of this disease in patients of different age groups, patients with chronic pathology, and pregnant women. Particular attention is paid to the post-COVID syndrome.

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Section: Mental Disordersmentioning

confidence: 99%

Section: Mental Disordersmentioning

confidence: 99%

Factors affecting the severity of COVID-19 and the development of complications

Radygina,

Mochalova

2023

Microbiology Independent Research Journal (MIR Journal)

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“…According to the findings of one study, infection with SARS-CoV-2 may be a cause of MDD [ 43 ]. In late December 2019, an epidemic of viral pneumonia caused by SARS-CoV-2, a novel coronavirus, was reported in Wuhan, China.…”

Section: Analysis Of the Mechanisms By Viruses That Affect Depressionmentioning

confidence: 99%

Exploring New Mechanism of Depression from the Effects of Virus on Nerve Cells

Wang

et al. 2023

Cells

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Depression is a common neuropsychiatric disorder with long-term recurrent depressed mood, pain and despair, pessimism and anxiety, and even suicidal tendencies as the main symptoms. Depression usually induces or aggravates the development of other related diseases, such as sleep disorders and endocrine disorders. In today’s society, the incidence of depression is increasing worldwide, and its pathogenesis is complex and generally believed to be related to genetic, psychological, environmental, and biological factors. Current studies have shown the key role of glial cells in the development of depression, and it is noteworthy that some recent evidence suggests that the development of depression may be closely related to viral infections, such as SARS-CoV-2, BoDV-1, ZIKV, HIV, and HHV6, which infect the organism and cause some degree of glial cells, such as astrocytes, oligodendrocytes, and microglia. This can affect the transmission of related proteins, neurotransmitters, and cytokines, which in turn leads to neuroinflammation and depression. Based on the close relationship between viruses and depression, this paper provides an in-depth analysis of the new mechanism of virus-induced depression, which is expected to provide a new perspective on the mechanism of depression and a new idea for the diagnosis of depression in the future.

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