The present paper is devoted to the proposal of appropriate numerical modelling able to provide a suitable description of the mechanical behavior of a composite geopolymer. Reference is made to a natural sisal-fiber-reinforced geopolymer. The study is based on the results of appropriate experimental investigations for compressive, flexural and splitting loadings, taking into account different weight percentages of fibers to evidence their role in the mechanical behavior. The main objective of the paper is to calibrate the microplane constitutive model, available in ANSYS software version 18.1, where the numerical analyses are performed. Therefore, the present study is structured in two different steps. Firstly, the mechanical behavior of geopolymers reinforced with sisal fibers is experimentally investigated, and subsequently, the gathered test data are interpreted and utilized to calibrate the relevant constitutive model to be used in the numerical stage. The obtained results are compared with experimental data, yielding good correlations. The paper’s results supply the parameters required to obtain an affordable numerical model of the reinforced geopolymer for different percentages of fibers to be adopted for material design with assigned mechanical properties.