2024
DOI: 10.1007/s44313-024-00036-4
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Absence of canonical mutations in pediatric essential thrombocytosis: a case series

Jae Wook Lee,
Suejung Jo,
Jae Won Yoo
et al.

Abstract: Essential thrombocytosis (ET) is a rare myeloproliferative disease in children, and there are few standard management guidelines. We herein report a case series of 10 pediatric patients with ET diagnosed at our institution over a period of 13 years. All patients fulfilled the World Health Organization diagnostic criteria for ET, and none harbored the canonical ET mutations JAK2 V617F, CALR, or MPL. Overall, 7 of the 10 patients received treatment for ET, and during follow-up, 3 of these 7 patients discontinued… Show more

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