Absence of Cognitive Impairment at Long-Term Follow-Up in Adolescents Treated With ECT for Severe Mood Disorder

Cohen, David; Taïeb, Olivier; Flament, Martine F.; Benoit, N.; Chevret, Sylvie; Corcos, Maurice; Fossati, Philippe; Jeammet, P.; Allilaire, Jean-Franæ®©s; Basquin, M.

doi:10.1176/appi.ajp.157.3.460

Cited by 116 publications

(55 citation statements)

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“…These results support other long-term studies that have found no cognitive differences at follow-up (Cohen et al 2000;Russell et al 2003). When we analyzed the results with a repeated-measures method, no significant interaction time · group was found.…”

Section: Discussionsupporting

confidence: 91%

“…Nevertheless, our study supports the research of Cohen et al (2000) with affective patients. Theirs was the only long-term follow-up study conducted with a sample of adolescent patients treated with ECT, and they found no differences in neuropsychological variables between the ECT group and a psychiatric comparison group.…”

Section: Discussionsupporting

confidence: 88%

“…However, the sample of that study was composed of patients with different diagnoses (schizophrenia, depression and bipolar disorder), and the assessment was performed during maintenance ECT. No long-term studies of verbal fluency are found in the literature, and other studies conducted with adolescent samples with severe mood disorders have found no significant differences in attention at long term follow-up (Cohen et al 2000;Russell et al 2003).…”

Section: Discussionmentioning

confidence: 92%

“…Only one study has analyzed cognitive effects of ECT in a sample of adolescents with a long-term follow-up (Cohen et al 2000). A sample of 10 adolescents in whom mood disorder was diagnosed were followed up until 3.5 years after the last ECT session and compared with 10 psychiatric comparison subjects.…”

Section: Introductionmentioning

confidence: 99%

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Two-Year Follow-Up of Cognitive Functions in Schizophrenia Spectrum Disorders of Adolescent Patients Treated with Electroconvulsive Therapy

Serna

Flamarique

Castro‐Fornieles

et al. 2011

Journal of Child and Adolescent Psychopharmacology

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Objective: The aim of the current study was to investigate the long-term cognitive effects of electroconvulsive therapy (ECT) in a sample of adolescent patients in whom schizophrenia spectrum disorders were diagnosed. Methods: The sample was composed of nine adolescent subjects in whom schizophrenia or schizoaffective disorder was diagnosed according to DSM-IV-TR criteria on whom ECT was conducted (ECT group) and nine adolescent subjects matched by age, socioeconomic status, and diagnostic and Positive and Negative Syndrome Scale (PANSS) total score at baseline on whom ECT was not conducted (NECT group). Clinical and neuropsychological assessments were carried out at baseline before ECT treatment and at 2-year follow-up. Results: Significant differences were found between groups in the number of unsuccessful medication trials. No statistically significant differences were found between the ECT group and the NECT group in either severity as assessed by the PANSS, or in any cognitive variables at baseline. At follow-up, both groups showed significant improvement in clinical variables (subscales of positive, general, and total scores of PANSS and Clinical Global Impressions-Improvement). In the cognitive assessment at follow-up, significant improvement was found in both groups in the semantic category of verbal fluency task and digits forward. However, no significant differences were found between groups in any clinical or cognitive variable at follow-up. Repeated measures analysis found no significant interaction of time · group in any clinical or neuropsychological measures. Conclusions: The current study showed no significant differences in change over time in clinical or neuropsychological variables between the ECT group and the NECT group at 2-year follow-up. Thus, ECT did not show any negative influence on long-term neuropsychological variables in our sample.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 92%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Two-Year Follow-Up of Cognitive Functions in Schizophrenia Spectrum Disorders of Adolescent Patients Treated with Electroconvulsive Therapy

Serna

Flamarique

Castro‐Fornieles

et al. 2011

Journal of Child and Adolescent Psychopharmacology

View full text Add to dashboard Cite

show abstract

“…Generally a decline in processing speed reported during ECT (58), but not decline in IQ. Cognitive functions are known to recover once ECT is completed and the recovery appears to be irrespective of the age of the patient (75). A recent review by the Food Drug Administration (FDA) found that cognitive function recovery following ECT may take up to six months after the completion of ECT (76).…”

Section: Discussionmentioning

confidence: 99%