639followed by a successful implantation of a drug eluting stent and final Thrombolysis in Myo cardial Infarction grade 3 flow (FIGURE 1A and 1B). A coronary angiogram showed the LCx giving off a significant branch that continued in the atrio ventricular groove. Moreover, an aortic root an giogram excluded the presence of an RCA ostium (FIGURE 1C). A year later, the patient was admitted for a control computed tomography angiogra phy (CTA), which confirmed patent LAD and LCx (FIGURE 1D and 1E), and an absent RCA (FIGURE 1F).To our knowledge, as few as 2 cases of an SCA in ACS have been reported so far. However, those patients revealed nonsignificant lesions in the cor onary arteries. 3 Observations from a Dutch co hort confirmed that SCAs were not free from atherosclerotic lesions, although no cases of ACS had been described. 2 The novelty of our report is that the culprit artery responsible for ACS may be within the SCA. The emerging role of CTA mayThe absence of a coronary artery is an extreme ly rare finding (incidence <0.01%). Until 2012, only 32 cases of an absent left circumflex cor onary artery (LCx) were reported, with an inci dence of around 0.003%. 1 The exact incidence of a congenital single coronary artery (SCA) with an absent right coronary artery (RCA) is unknown, with only several such anomalies having been de scribed. Most of those cases were reported as in cidental angiographic findings, and a Dutch an giographic series of 15 cases is probably the larg est SCA cohort so far. 2 Acute coronary syndrome (ACS) with a culprit lesion in the SCA seems to be extremely rare and, to our best knowledge, has not been reported so far.A 40 year old woman with metabolic syndrome underwent primary percutaneous coronary in tervention for ST segment elevation myocardial infarction of the anterior wall. The left anterior descending coronary artery (LAD) was opened,
CLINICAL IMAGEAcute coronary syndrome with a culprit lesion in a single coronary artery