1989
DOI: 10.1097/00005344-198900148-00011
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Absence of Proarrhythmic Effects of Ibopamine in Patients with Congestive Heart Failure

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Cited by 13 publications
(7 citation statements)
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“…Ibopamine 100mg 3 times daily for 5 or 7 days had no clinically significant influence on cardiac rhythm in more than 100 patients with congestive heart failure who were free of severe arrhythmias at baseline (Caponnetto et al 1989;Furlanello et al 1989). Atrioventricular and intraventricular conduction times, QT interval, supraventricular ectopic beat and couplet frequency, ventricular ectopic beat frequency, Lown class and the number of patients with> 10 supraventricular runs of tachycardia per 24 hours did not show any significant difference between ibopamine and placebo treatment.…”
Section: Electrophysiological Effectsmentioning
confidence: 99%
“…Ibopamine 100mg 3 times daily for 5 or 7 days had no clinically significant influence on cardiac rhythm in more than 100 patients with congestive heart failure who were free of severe arrhythmias at baseline (Caponnetto et al 1989;Furlanello et al 1989). Atrioventricular and intraventricular conduction times, QT interval, supraventricular ectopic beat and couplet frequency, ventricular ectopic beat frequency, Lown class and the number of patients with> 10 supraventricular runs of tachycardia per 24 hours did not show any significant difference between ibopamine and placebo treatment.…”
Section: Electrophysiological Effectsmentioning
confidence: 99%
“…The study enrolled only very severely affected patients (class IV) and was mostly focused on prognosis and func tional classification [12]. Other long-term studies which examined patients with differ ent severity of heart failure either enrolled younger patients than our sample or were unblinded [23][24][25][26],…”
Section: Discussionmentioning
confidence: 99%
“…and in a third period ibopamine 200 mg t.i.d. With both doses the number of extrasystoles and Lown classification de creased [16]. This finding, however, cannot be used because of the insufficient study pro tocol.…”
Section: Electrophysiological Studiesmentioning
confidence: 91%