Absence seizures in children and teenagers: ethosuximide, valproate or lamotrigine? A systematic review from 1999 to 2021 / Apreensões de ausência em crianças e adolescentes: etosuximida, valproato ou lamotrigina? Uma revisão sistemática de 1999 a 2021

Abstract

The onset of AS generally occurs during childhood or adolescence, and it is the most prevalent convulsion in 15 to 20% of epileptic children. Historically, first-line drugs in pediatric AS are Ethosuximide (ETX), Valproic Acid (VPA), and Lamotrigine (LTG). This review aims to determine the best pharmacological therapy for pediatric AS, considering that all three drugs have been established as superior to placebo.