“…Cases of early-onset TAS have been previously published (Caraballo et al, 2011;Giordano et al, 2013). De novo ASE has been reported more often in adult patients than in children (Agathonikou et al, 1998;Grin and DiMario, 1998;Genton et al, 2008;Bilo et al, 2014;Fisher et al, 2014;Adams et al, 2016;Paschen et al, 2016;Brigo et al, 2018). As to paediatric patients, our three patients and the only two children previously published in the literature (Grin and DiMario, 1998;Adams et al, 2016) had de novo ASE without experiencing absence seizures before the episode or during their follow-up, except for one (Grin and DiMario, 1998) who presented a typical absence event after the ASE.…”