Absorption and metabolism of polyphenols in the gut and impact on health

In this study sour cherry pomace was extracted with food-grade solvent (50% ethanol), concentrated and stabilized in whey and soy proteins by encapsulation. Soy proteins exhibited higher encapsulation efficiency (94.90%), but not significantly (p < 0.05), from whey (90.10%). Storage properties of whey (WP) and soy protein (SP) encapsulates in terms of total polyphenols, anthocyanins and antioxidant activity were tested for 6 weeks. At the end of storage period the retention of polyphenols in SP and WP was similar (67.33 and 69.30%, respectively), while the content of anthocyanins has increased in SP (for 47.97%) and decreased in WP (for 1.45%). The decrease in antioxidant activity in SP (12.22%) was lower than in WP (35.04%). Colour parameters of encapsulates have followed the similar trend as anthocyanin change during storage. The technique reported herewith can be used for obtaining quality encapsulates for their use as functional food additives, as a way of fruit waste valorization.

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“…non-conjugated polyphenols). 3 Additionally, high molecular weight polyphenols (tannins, proanthocyanidins etc.) cannot be easily absorbed.…”

Section: Introductionmentioning

confidence: 99%

Encapsulation of sour cherry pomace extract by freeze drying: characterization and storage stability

Šaponjac

Ćetković

Čanadanović-Brunet

et al. 2017

ACSi

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“…First, the phenolic compounds from ryegrass were not absorbed in the digestive tract of lambs or they were quickly excreted in the urine. Indeed, the bioavailability of these polyphenols in ruminants is as yet unknown and, in monogastric animals, it has been reported that most dietary polyphenols are quickly eliminated in both the urine and bile after ingestion (Scalbert et al, 2002). Second, flavonoids from grass could have been absorbed in the gastrointestinal tract, but had already been excreted by the time the sampling was carried out.…”

Section: Discussionmentioning

confidence: 99%

Antioxidant effects of ryegrass phenolics in lamb liver and plasma

Luciano

Vasta

Gibson

et al. 2014

Animal

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Sixteen lambs were divided into two groups and fed two different diets. Eight lambs were stall-fed with a concentrate-based diet (C), and the remaining eight lambs were allowed to graze on Lolium perenne (G). The antioxidant status was measured in the liver and plasma samples before and after solid-phase extraction (SPE) to probe the antioxidant effects that grass phenolic compounds may have conferred onto the animal tissues. The liver and plasma samples from grass-fed lambs displayed a greater antioxidant capacity than the tissues from C lamb group, but only if samples had not been passed through SPE cartridges. Finally, the feed and animal tissues, which had been purified by SPE, were analysed by liquid chromatography combined with mass spectrometry (LC-MS) to identify phenolic compounds present in L. perenne and to evaluate the results from the antioxidant assays. It would appear that the improvement of the antioxidant capacity of lamb liver and plasma from lambs fed ryegrass was not related to the direct transfer of phenolic compounds from grass to the animal tissues.

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“…No entanto, acredita-se que estes flavonóides intactos sejam pouco absorvidos pelo trato gastrointestinal, em função do seu elevado peso molecular, mas poderiam alcançar o cólon onde seriam metabolizados pela microflora intestinal. A atividade biológica dos metabólitos produzidos, que poderia ser exercida no pró-prio trato gastrointestinal (TGI), tem sido pouco estudada até o momento (SCALBERT et al, 2002). Assim, as proantocianidinas, que são polímeros de flavonóides com grau variável de polimerização, aparentemente contribuem pouco com a atividade biológica na fase pós-absortiva.…”

Section: Compostos Fenólicos Totais (Cft) Nas Frações Solúvel E Insolunclassified

“…Os de menor peso molecular, em especial os ácidos fenólicos, parecem ser facilmente absorvidos no intestino delgado onde são conjugados para ο-glicorunídeos, ésteres de sulfato e ο-metiléter. A absorção tem sido demonstrada indiretamente pelo aumento da capacidade antioxidante do plasma ( BOURNE; RICE-EVANS, 1998;ADAM et al, 2002;SCALBERT et al, 2002;TAPIERO et al, 2002;ZHAO, EGASHIRA;SANADA, 2003SANADA, e 2004.…”

Section: Quantificação Dos áCidos Fenólicosunclassified

Extração, análise e distribuição dos ácidos fenólicos em genótipos pigmentados e não pigmentados de arroz (Oryza sativa L.)

Mira¹,

Barros²,

Schiocchet³

et al. 2008

Ciênc. Tecnol. Aliment.

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Cereais integrais têm um papel importante na nutrição humana. Dentre estes, o arroz, importante commodity agrícola que representa um quarto da produção mundial de grãos é responsável por 20% do suprimento calórico da dieta, enquanto o trigo e o milho provêem 19 e 5%, respectivamente (FAO, 2004).A Organização das Nações Unidas para Agricultura e Alimentação (FAO, 2004) calcula que o arroz é consumido por cerca de três bilhões de pessoas, correspondendo à metade da população mundial e, segundo estimativas oficiais no Brasil, até 2050 haverá uma demanda para atender ao dobro desta população (BRASIL, 2007; EMBRAPA, 2006).Estudos epidemiológicos sugerem que a ingestão regular de grãos integrais reduz o risco de doenças crônicas associadas a danos oxidativos, como doenças cardiovasculares, câncer e outras patologias (SLAVIN, 2004;ARTS;HOLLMAN, 2005). Em vista da contínua promoção dos benefícios funcionais e de saúde, o consumo de arroz integral vem sendo estimulado por AbstractThis study was conducted to evaluate the distribution of total phenolic compounds and phenolic acids in the soluble and insoluble fractions of 10 rice (Oryza sativa L.) genotypes with pigmented or non-pigmented pericarp. These compounds were reported to exert beneficial effects on human health due to their high antioxidant activities. The total phenolic compounds (CFT) in both fractions was determined by the Folin-Ciocalteau method and phenolic acids RP-HPLC with Diode-Array Detection (DAD) in order to analyze phenolic acids. The amount of CFT in the soluble fraction was about 5.7 times higher in pigmented than in non-pigmented genotypes showing mean values of 3468 and 602 µg eq.ferulic acid/g rice, respectively. The presence of proanthocyanidins and anthocianins seems to be responsible for the higher amounts. The average amounts of CFT in the insoluble fraction was two-fold higher in the pigmented than in the non pigmented genotypes (825 e 378 μg eq. ferulic acid/g rice, respectively) probably due to the retention of antocyanidins and proanthocyanidins even after five consecutive extractions. Among the phenolic acids, the ferulic acid was the major phenolic acid found among all genotypes analyzed, except for the black pericarp in which the protocatechuic acid was predominant.

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Absorption and metabolism of polyphenols in the gut and impact on health

Cited by 613 publications

References 62 publications

Encapsulation of sour cherry pomace extract by freeze drying: characterization and storage stability

Encapsulation of sour cherry pomace extract by freeze drying: characterization and storage stability

Antioxidant effects of ryegrass phenolics in lamb liver and plasma

Extração, análise e distribuição dos ácidos fenólicos em genótipos pigmentados e não pigmentados de arroz (Oryza sativa L.)

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