Absorptive Capacity for Dietary Fat in Elderly Patients With Debilitating Disorders

Simko, Vlado; Michael, Shoukry

doi:10.1001/archinte.1989.00390030055010

Cited by 23 publications

(3 citation statements)

References 25 publications

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“…This suggests that the capacity to absorb and accumulate dietary fat into plasma chylomicrons in older individuals is comparable to that in younger individuals. This argument is in line with more direct findings from other studies that indicate that the absorption of dietary fat is not affected by age (26)(27)(28).…”

Section: Absorption Of Dietary Fatsupporting

confidence: 91%

Clinical Considerations and Mechanistic Determinants of Postprandial Lipemia in Older Adults

Katsanos

2014

Advances in Nutrition

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The typical diet of individuals in Western societies results in metabolic responses associated with fed-state fat metabolism for most of the daily life of the individual. This fat metabolism is characterized specifically by an increase in the concentration of plasma lipids, primarily triglycerides. Increased postprandial lipemia, which is typically observed in older individuals (i.e., >65 y old), has now emerged as an important correlate of cardiovascular disease risk. An understanding of the mechanisms contributing to the increased postprandial lipemia in older individuals becomes, therefore, of particular clinical importance in any effort to explain and address the well-documented increase in cardiovascular disease risk as individuals age. Current evidence points to an increase in the accumulation of ingested lipid in lipoprotein particles of hepatic origin, together with an overall accumulation of lipid in these lipoproteins during the postprandial period, as primary contributors to the postprandial lipemia in older persons. When this evidence is considered together with the evidence suggesting large atherogenic potential of lipoproteins of hepatic origin, this can, at least in part, explain the increased risk of cardiovascular disease in older individuals. Understanding changes in the metabolism of ingested fat in the immediate postprandial period with advancing age, and how lifestyle interventions such as diet and physical exercise can ameliorate the increase in postprandial lipemia in older individuals, is important in order to address the increased cardiovascular disease risk in this particularly affected and growing segment of the population.

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Section: Absorption Of Dietary Fatsupporting

confidence: 91%

Clinical Considerations and Mechanistic Determinants of Postprandial Lipemia in Older Adults

Katsanos

2014

Advances in Nutrition

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“…Our reasons are that the subjects in this study (1) However, the results of several studies3-4 have clearly suggested that the pancreas and gut of aging rats do not adapt to changes in dietary intake as well as in young rats. We agree that in routine realimentation there is no reason to exclude a liberal amount of dietary fat.…”

Section: Tube Feeding In Elderly Patients Tube Feeding In Elderly Patmentioning

confidence: 87%

Tube Feeding in Elderly Patients

CHUMLEA¹

1990

Arch Intern Med

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“…High-fat (up to 50%) enteral foods are advised to patients with chronic obstructive pulmonary disease (COPD) (Noller and Mobarhan, 1986). Such foods are reported to be well tolerated, even by debilitated elderly patients (Simko and Shoukry, 1989). The beneficial effects of high-fat formula for patients with abnormal glucose tolerance and COPD have been reported by Brandstetter et al (1988).…”

Section: Disease-specific Formulaementioning

confidence: 90%

Medical Foods from Natural Sources

Kaur¹

2009

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Absorptive Capacity for Dietary Fat in Elderly Patients With Debilitating Disorders

Cited by 23 publications

References 25 publications

Clinical Considerations and Mechanistic Determinants of Postprandial Lipemia in Older Adults

Clinical Considerations and Mechanistic Determinants of Postprandial Lipemia in Older Adults

Tube Feeding in Elderly Patients

Medical Foods from Natural Sources

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