Abstract:Pancreatic ductal adenocarcinoma (PDAC) is one of the most deadly human malignancies. The only curative treatment available is the surgical removal of the tumor in early stages of the disease. Current methods for early detection and treatment are poor, justifying more studies in this field. We aim to generate a high-resolution catalog of the PDAC transcriptome, to reveal transcriptional alterations associated with the malignant phenotype of PDAC. To that end 28 patient matched samples of PDAC and nontumor adja… Show more
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