2015
DOI: 10.1158/1538-7445.am2015-5055
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Abstract 5055: Role of insulin-like growth factor 1 receptor in pancreatic cancer pathogenesis

Abstract: Pancreatic cancer incidence and the associated mortality are increasing worldwide. This indicates that there is a clear lack of understanding about pancreatic cancer pathogenesis. This can be attributed to the lack of specific symptoms to diagnose the disease at an early stage. Various growth factor receptors are known to play a vital role in the development of pancreatic cancer. In the present investigation, we have attempted to target insulin-like growth factor-1 receptor (IGF-1R) due to its well-established… Show more

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