Abstract 5548: Clinical management and decision making in early ER-positive breast cancers through improved prognosis and pathway directed molecular profiling
Abstract:Hormone receptor positive (HR+ve) breast cancer (BCa) comprises over 80% of all newly diagnosed BCas. While there is an initial good response to anti-hormone therapies, many patients will experience a recurrence. Validated prognostic tests are used to guide chemotherapy decisions, but the goal of precision medicine has yet to be achieved. We developed and validated a 95-gene prognostic signature (Bayani et al 2017) from the TEAM trial (van de Velde et al, 2011), demonstrating this risk classifier performed as … Show more
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