2012
DOI: 10.1161/hyp.60.suppl_1.a651
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Abstract 651: Genetic Mapping Of Traits And Transcriptome In The Lyon Hypertensive Rat

Abstract: The metabolic syndrome (MetS) is characterized by obesity, dyslipidemia, hypertension, and insulin resistance and is a major risk factor for cardiovascular disease. Using the Lyon Hypertensive and Lyon Normotensive rats as models of the metabolic syndrome, we aim to determine both physiological and transcriptional regulation underlying the syndrome. To identify genetic loci influencing phenotypes underlying MetS, an F2 intercross between LH and LN with 150 offspring was studied to identify physiological quanti… Show more

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