Abstract:BDX004 is a multivariate serum proteomics companion diagnostic (CDx) test currently under development as part of a global, randomized, double-blind Phase 2 clinical study, FOCAL. The test will be used prospectively to select previously untreated, EGFR mut-positive patients with advanced NSCLC to receive one of two treatments: (1) the combination of ficlatuzumab (a humanized mAb against hepatocyte growth factor) and an EGFR tyrosine kinase inhibitor (TKI), or (2) an EGFR TKI with placebo. BDX004 measures the ab… Show more
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