Abstract ES8-2: ES8-2 Energy balance: The new adjuvant therapy?

Abstract

Obesity affects the risk of breast cancer development and the risk of recurrence and death from breast cancer. Furthermore, weight gain after diagnosis of breast cancer (independent of BMI at diagnosis) is associated with higher all-cause mortality rates compared with maintaining body weight. The American Cancer Society (ACS) recommends cancer survivors achieve and maintain a healthy weight, follow a dietary pattern high in vegetables, fruits, and whole grains, engage in 150 minutes per week of aerobic exercise plus two strength training sessions per week, and avoid physical inactivity. Despite these recommendations, over 65% of breast cancer survivors are overweight or obese, and fewer than 30% engage in recommended levels of physical activity. Recently, the American Society of Clinical Oncology (ASCO) published a position statement on obesity and cancer with a multipronged initiative to reduce the impact of obesity on cancer, with one of the initiatives focused on determining best methods to help cancer survivors make effective changes in lifestyle behaviors. The impact of weight loss and exercise trials on breast cancer outcomes, as well as future research opportunities and the role of clinical and community-based weight management programs, will be discussed. Citation Format: Irwin ML. ES8-2 Energy balance: The new adjuvant therapy? [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr ES8-2.