At present, the existing teaching construction information fusion methods are based on the classification results of teaching resources, but ignoring the global intelligent optimization of the fusion results, which leads to the deviation of the grassroots teaching organization construction information fusion results, and the fusion index value is low. Therefore, the information fusion method of the grassroots teaching organization construction based on intelligent optimization is proposed. The basic framework of information fusion is designed, and the information fusion is divided into the data layer, characteristic layer, and decision layer. The information characteristics of the construction of grassroots teaching organizations were extracted. The particle swarm optimization algorithm is used to search the maximum value of the work entropy of teaching grassroots unit, and the threshold value of teacher construction and grassroots unit work is used to realize the information fusion of teaching grassroots unit construction. Experimental results show that the proposed method has higher error rate, stability, efficiency index, and higher information fusion value and accuracy than the traditional method.