Acalculous Cholecystitis in Viet Nam Casualties

Lindberg, Evan F.; Grinnan, George L.B.; Smith, Lawrence

doi:10.1097/00000658-197001000-00022

Cited by 100 publications

(28 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Acute acalculous cholecystitis tends to accompany sys temic disorders associated with acute hypoperfusion [17][18][19]: in the current study, 32% of the patients had suffered septic shock, 21% multitrauma and 10% had developed the acalculous cholecystitis following surgery. Diagnosis is often delayed since there is usually no previous gallblad der history (69%) and the acute ischemic cholecystitis is part of a systemic disease.…”

Section: Discussionmentioning

confidence: 46%

Ischemic Cholecystitis – Gangrenous, Perforated and Acalculous Cholecystitis

Goldman¹,

Kahn²,

Halpern

et al. 1993

Dig Surg

View full text Add to dashboard Cite

The charts of 200 patients with acute inflammatory gallbladder disease were reviewed. Forty-eight patients were found with grangrenous, perforated or acalculous cholecystitis. These three conditions resulting from an ischemic gallbladder, differ from simple acute cholecystitis in its pathogenesis, laboratory findings and clinical course. Gangrenous and perforated cholecystitis accompany chronic systemic vascular compromise, whereas acalculous cholecystitis is found in a severe acute low-flow state. Awareness, together with careful clinical history, physical examination, selective blood tests and high-quality ultrasound, all contribute in the accurate diagnosis of this neglected condition. Intensive perioperative management is recommended.

show abstract

Section: Discussionmentioning

confidence: 46%

Ischemic Cholecystitis – Gangrenous, Perforated and Acalculous Cholecystitis

Goldman¹,

Kahn²,

Halpern

et al. 1993

Dig Surg

View full text Add to dashboard Cite

show abstract

“…Golden et al [3] first suggested that 392 H assc/Zielke/N ics/Al-Bazaz/Gotzen/ Rothmund ACC may be a result of a multitude of different factors, and recognized stasis in the biliary tree as the essential factor in the pathogenesis. Decrease in biliary motility causes thickening of bile and subsequent sludge forma tion, dilation of the gallbladder, edema of tissue and, finally, results in hypoperfusion of the gallbladder wall [2,30,31], Although these factors are well accepted, the exact mechanism responsible for the disturbance of biliary mo tility still is a matter of debate. In order to treat biliary stasis, a variety of drugs is under continued investigation.…”

Section: Discussionmentioning

confidence: 99%

Influence of Ceruletid on Gallbladder Contraction: A Possible Prophylaxis of Acute Acalculous Cholecystitis in Intensive Care Patients?

Hasse¹,

Zielke²,

Nies³

et al. 1995

Digestion

View full text Add to dashboard Cite

The purpose of this study was to investigate the utility of repeated applications of ceruletid to reduce gallbladder volume and its feasibility as a means of prophylaxis of acute acalculous cholecystitis in intensive care patients. First, a dose-response curve of ceruletid was obtained in 20 mechanically ventilated patients of a surgical intensive care unit (SICU) not receiving enteral nutrition. An effective dose of ceruletid, defined by a 50% reduction of gallbladder volume was established and subsequently studied in 40 mechanically ventilated SICU patients on total parenteral nutrition in a prospective, randomized, controlled, triple-blind trial. Gallbladder volume, sludge formation and side effects were evaluated. A dose of 1.5 μg/kg body weight ceruletid was established as the effective dose, causing 50% reduction of gallbladder volume in all patients studied and reduction of gallbladder sludge in 95%. In 67.5% of patients side effects were observed, requiring therapeutic intervention in 68%. It is concluded that ceruletid is effective in stimulating gallbladder contraction and reducing sludge formation in severely ill patients on intensive care units. Its routine use as prophylaxis of acute acalculous cholecystitis, however, may be limited by the nature, severity and frequency of side effects.

show abstract

“…A multitude of predisposing factors such as acute illness in childhood, specific fevers, extensive burns, polytrauma, and major sur› gical procedures (non-biliary) have been at› tributed as the cause [1,2,[4][5][6]. The patho› genesis which is probably multifactorial in› cludes a possible biliary stasis, increased bile viscocity and lithogenicity, and gall bladder ischaemia [1,7].…”

Section: Discussionmentioning

confidence: 99%

Acute Acalculous Cholecystitis

Singh

1995

Medical Journal Armed Forces India

View full text Add to dashboard Cite

Acalculous Cholecystitis in Viet Nam Casualties

Cited by 100 publications

References 3 publications

Ischemic Cholecystitis – Gangrenous, Perforated and Acalculous Cholecystitis

Ischemic Cholecystitis – Gangrenous, Perforated and Acalculous Cholecystitis

Influence of Ceruletid on Gallbladder Contraction: A Possible Prophylaxis of Acute Acalculous Cholecystitis in Intensive Care Patients?

Acute Acalculous Cholecystitis

Contact Info

Product

Resources

About