Acaricidal Activity ofPaeonia suffruticosaRoot Bark-Derived Compounds againstDermatophagoides farinaeandDermatophagoides pteronyssinus(Acari:  Pyroglyphidae)

Abstract

The acaricidal activities of materials derived from the root bark of Paeonia suffruticosa against adults of Dermatophagoides farinae and Dermatophagoides pteronyssinus were examined using direct contact and fumigation bioassays and compared with those of benzyl benzoate, dibutyl phthalate, and N,N-diethyl-m-toluamide (deet), widely used acaricides. The active constituents of Paeonia root bark were identified as paeonol and benzoic acid by spectroscopic analyses. On the basis of 24-h LD50 values, the acaricidal activities of paeonol (7.82 microg/cm3) and benzoic acid (6.58 microg/cm3) against adult D. farinae were comparable to that of benzyl benzoate (7.72 microg/cm3) but higher than those of deet (36.34 microg/cm3) and dibutyl phthalate (33.92 microg/cm3). Against adult D. pteronyssinus, the acaricidal activities of paeonol (7.08 microg/cm3) and benzyl benzoate (7.22 microg/cm3) were comparable to that of benzyl benzoate (7.14 microg/cm3). Deet and dibutyl phthalate were less effective. In fumigation tests with both mite species, paeonol and benzoic acid were much more effective in closed containers than open ones, indicating that the effect of these compounds was largely a result of action in the vapor phase. Neither benzyl benzoate, deet, nor dibutyl phthalate exhibited fumigant toxicity. Paeonia root bark-derived materials, particularly paeonol and benzoic acid, merit further study as potential acaricides or lead compounds for the control of D. farinae and D. pteronyssinus.

Floral Scent Chemistry of Luculia yunnanensis (Rubiaceae), a Species Endemic to China with Sweetly Fragrant Flowers

“…In addition, some compounds of floral VOCs had a good effect on resisting bacteria and fungus [ 7 , 16 , 17 ]. Amongst the floral scent composition of L. yunnanensis , phenylethyl alcohol has antifungal activity against Botrytis cinerea [ 18 ]; limonene oxide has antibacterial activities against Agrobacterium tumefaciens , Erwinia ananas , Erwinia chrysanthemi , and Enterobacter cloacae [ 19 ]; paeonol has potential acaricide activity for the control of Dermatophagoides pteronyssinus and Dermatophagoides farina [ 16 ]. From this point of view, L. yunnanensis might be qualified as an indoor fragrant houseplant.…”

Volatile Organic Compounds Emissions from Luculia pinceana Flower and Its Changes at Different Stages of Flower Development

“…Some of volatile compounds from flowers are pharmacologically active compounds. For example, paeonol has several interesting biological activities, and it has been used as an anti-inflammatory, analgesic, antioxidant, antidiabetic, and acaricidal agent [13,14]; cyclosativene demonstrates strong anti-inflammatory, expectorant, antifungal effect [15]; γ-muurolene and δ-cadinene have antifungal properties. Despite the fact that essential oils are seldom encountered in the Rubiaceae [16], L. pinceana would have a lot of potential for essential oil extraction according to the L. pinceana solid phase microextraction results.…”

Integrated Profiling of Fatty Acids, Sterols and Phenolic Compounds in Tree and Herbaceous Peony Seed Oils: Marker Screening for New Resources of Vegetable Oil

“…As an example, benzoic, gallic and caffeic acids were reported in the seeds of all the nine tree peony species native to China [15]. Paeonol and benzoic acid were found to be the active constituents (with acaricidal activity) of Paeonia suffruticosa root bark by spectroscopic analyses [16].…”