This work, realized in the framework of the European project TurboNoiseBB, presents an advanced aeroacoustic design methodology of Outlet Guide Vanes (OGVs) with leading edge serrations, including details on their broadband noise and aerodynamic performance. The serrated OGV corresponds to a modified stator from an aero-engine fan stage tested at the AneCom Aerotest's facility (Germany). Sinusoidal leading edge patterns with varying amplitude and wavelength along the span are designed in collaboration with Safran Aircraft Engines. Serrations are adjusted to account for the turbulence characteristics provided by Reynolds-Averaged Navier-Stokes (RANS) calculations. Optimal parameters are found using simple design rules discussed in the paper. Down selection of serrated OGV designs (patent pending) are conducted through a RANS control of aerodynamic performances and in accordance with industrial specifications, ensuring acceptable penalties on the loss coefficient and isentropic efficiency. Broadband noise simulations are performed using a computational aeroacoustic (CAA) code that solves the linearized Euler equations with a synthetic turbulence model. Additionally, the acoustic response of the serrated leading edge airfoils is also estimated using the most relevant analytical formulation in the literature, based on the Wiener-Hopf technique. Numerical predictions at approach conditions are compared to available experimental measurements (on the untreated baseline case) and analytical Amiet-based and Wiener-Hopf solutions, showing a satisfactory agreement in the sound power spectrum in the bypass duct. Finally, the acoustic performances estimated at the design stage are numerically assessed by both CAA and Wiener-Hopf methods, providing around 2.5 dB and 3.5 dB reduction on the overall power level, respectively.