ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult

Hunt, Sharon A.; Abraham, William T.; Chin, Marshall H.; Feldman, Arthur M.; Francis, Gary S.; Ganiats, Théodore G.; Jessup, Mariell; Konstam, Marvin A.; Mancini, Donna; Michl, Keith; Oates, John A.; Rahko, Peter S.; Silver, Marc A.; Stevenson, Lynne Warner; Yancy, Clyde W.; Antman, Elliott M.; Smith, Sidney C.; Adams, Cynthia D.; Anderson, Jeffrey L.; Faxon, David P.; Fuster, Valentín; Halperin, Jonathan L.; Hiratzka, Loren F.; Jacobs, Alice K.; Nishimura, Rick A.; Ornato, Joseph P.; Page, Richard L.; Riegel, Bárbara

doi:10.1161/circulationaha.105.167586

Cited by 1,971 publications

(798 citation statements)

References 755 publications

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“…To evaluate trends after the 2005 and 2009 ACC/AHA guideline updates for the management of HF in adults,15, 16 we additionally evaluated trends in 3 intervals demarcated by the guideline‐release years (ie, 2001–2005, 2006–2009, and 2010–2014). Change in trend from one interval to the next (ie, between 2 adjoining intervals) was evaluated via piece‐wise regression modeling with robust variance.…”

Section: Methodsmentioning

confidence: 99%

National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014)

Akintoye

Briasoulis

Egbe

et al. 2017

JAHA

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BackgroundTo investigate heart failure (HF) hospitalization trends in the United States and change in trends after publication of management guidelines.Methods and ResultsUsing data from the National Inpatient Sample and the US Census Bureau, annual national estimates in HF admissions and in‐hospital mortality were estimated for years 2001 to 2014, during which an estimated 57.4 million HF‐associated admissions occurred. Rates (95% confidence intervals) of admissions and in‐hospital mortality among primary HF hospitalizations declined by an average annual rate of 3% (2.5%–3.5%) and 3.5% (2.9%–4.0%), respectively. Compared with 2001 to 2005, the average annual rate of decline in primary HF admissions was more in 2006 to 2009 (ie, 3.4% versus 1.1%; P=0.02). In 2010 to 2014, primary HF admission continued to decline by an average annual rate of 4.3% (95% confidence interval, 3.9%–5.1%), but this was not significantly different from 2006 to 2009 (P=0.14). In contrast, there was no further decline in in‐hospital mortality trend after the guideline‐release years. For hospitalizations with HF as the secondary diagnosis, there was an upward trend in admissions in 2001 to 2005. However, the trend began to decline in 2006 to 2009, with an average annual rate of 2.4% (95% confidence interval, 0.8%–4%). Meanwhile, there was a consistent decline in in‐hospital mortality by an average annual rate of 3.7% (95% confidence interval, 3.3%–4.2%) during the study period, but the decline was more in 2006 to 2009 compared with 2001 to 2005 (ie, 5.4% versus 3.4%; P<0.001). Beyond 2009, admission and in‐hospital mortality rates continued to decline, although this was not significantly better than the preceding interval.ConclusionsFrom 2001 to 2014, HF admission and in‐hospital mortality rates declined significantly in the United States; the greatest improvements coincided with the publication of the 2005 American College of Cardiology/American Heart Association HF guidelines.

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Section: Methodsmentioning

confidence: 99%

National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014)

Akintoye

Briasoulis

Egbe

et al. 2017

JAHA

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“…2005). The present etiology of HF is mainly associated with myocardial ischemia or infarction due to coronary artery diseases (Hunt et al.…”

Section: Introductionmentioning

confidence: 99%

“…The present etiology of HF is mainly associated with myocardial ischemia or infarction due to coronary artery diseases (Hunt et al. 2005). Ischemic HF occurs in more than 60% HF patients and leads to a high global burden (Moran et al.…”

Section: Introductionmentioning

confidence: 99%

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The Structure-function remodeling in rabbit hearts of myocardial infarction

Niu

et al. 2017

Physiol Rep

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Animal models are of importance to investigate basic mechanisms for ischemic heart failure (HF). The objective of the study was to create a rabbit model through multiple coronary artery ligations to investigate the postoperative structure‐function remodeling of the left ventricle (LV) and coronary arterial trees. Here, we hypothesize that the interplay of the degenerated coronary vasculature and increased ventricle wall stress relevant to cardiac fibrosis in vicinity of myocardial infarction (MI) precipitates the incidence and progression of ischemic HF. Echocardiographic measurements showed an approximately monotonic drop of fractional shortening and ejection fraction from 40% and 73% down to 28% and 58% as well as persistent enlargement of LV cavity and slight mitral regurgitation at postoperative 12 weeks. Micro‐CT and histological measurements showed that coronary vascular rarefaction and cardiac fibrosis relevant to inflammation occurred concurrently in vicinity of MI at postoperative 12 weeks albeit there was compensatory vascular growth at postoperative 6 weeks. These findings validate the proposed rabbit model and prove the hypothesis. The post‐MI rabbit model can serve as a reference to test various drugs for treatment of ischemic HF.

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“…1 Despite advances in pharmacologic therapy with angiotensin-converting enzyme inhibitors, β-blockers, and aldosterone antagonists, 2 -6 patients with HF account for over 12-15 million office visits and over 6.5 million hospital days each year. 7 Patients hospitalized for HF are at high risk for readmission, with a 6-mo readmission rate as high as 50%. 8 Studies show that comprehensive discharge planning, including medication counseling and review along with increased communication and follow-up, can help reduce readmissions.…”

Section: Introductionmentioning

confidence: 99%

Current trends in heart failure readmission rates: analysis of medicare data

Aranda

Johnson

Conti

2009

Clinical Cardiology

100

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Background: Despite advances in optimal pharmacologic therapy, patients with heart failure (HF) continue to have significant rehospitalization rates. Hypothesis: We sought to provide current estimates on rates of readmission for Medicare patients with HF, and identify factors associated with an increased chance of readmission. Methods: We used Medicare data from the 5% sample Standard Analytical File Limited Data Set for the years 2002 through 2004 to calculate readmission rates for HF. Clinical factors associated with readmission rates were identified using multivariate logistic regression. Results: We identified 28,919 patients accounting for 38,849 HF hospitalizations in the 5% sample for 2003. These numbers project to an estimated 578,380 patients with 776,980 HF hospitalizations. In-hospital mortality was 4.4% with an average length of stay of 5.5±5.4 d. In the 6-9 mo following the initial HF admission, 60% of patients had 1 or more readmissions for any cause. Heart failure accounted for 28% of all readmissions. Factors associated with readmission for HF after the initial HF hospitalization included age <65 y, geographic location, previous hospitalization, length of stay of initial HF hospitalization >7 d, not receiving a cardiac device implant at the time of initial HF hospitalization, and history of comorbidities including diabetes, myocardial infarction, peripheral vascular disease, and stroke. Conclusions: Medicare patients with HF continue to have significant morbidity and one of the highest inhospital mortality rates of any HF patient population. Factors associated with worse outcomes after an initial HF hospitalization can be used to identify patients who require aggressive therapy and follow-up.

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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult

Cited by 1,971 publications

References 755 publications

National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014)

National Trends in Admission and In‐Hospital Mortality of Patients With Heart Failure in the United States (2001–2014)

The Structure-function remodeling in rabbit hearts of myocardial infarction

Current trends in heart failure readmission rates: analysis of medicare data

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