A 65 years old woman with hypertension, diabetes mellitus and history of coronary artery bypass grafting presented with abdominal pain, nausea, vomiting since two days and one day history of maroon colored bowel movements. Her blood pressure was 190/100 and her abdomen was diffusely tender. Urgent CT scan with intravenous contrast detected thrombosis of the Superior Mesenteric Artery (SMA) but no bowel wall edema or pneumatosis intestinalis (air within bowel wall). The patient, therefore, underwent emergent, percutaneous intervention consisting of a challenging aspiration thrombectomy followed successfully by angioplasty and bare metal stent placement. The patient tolerated the procedure well and was discharged from the hospital. She did not need any small or large intestinal resection which is usually expected even after a successful percutaneous intervention [1] re-iterating the importance of timely successful intervention in this patient population to prevent major morbidity and mortality.
DiscussionAcute thrombo-embolic occlusion of the SMA leads to intestinal infarction and is associated with a mortality rate of around 65% [2]. The key to salvage ischemic bowel and prevent patient death is rapid revascularization as well as early diagnosis before bowel ischemia progresses to irreversible bowel necrosis. Therefore, early clinical and radiological diagnosis and appropriate treatment is required for a good prognosis. The primary goal of therapy is rapid and complete restoration of SMA flow and hopefully preserve entire bowel viability. Surgery such as SMA embolectomy, revascularization, SMA bypass, and resection of necrotic bowel, have been attempted, but the peri-operative mortality still remains more than 50% [3]. Failed thrombolysis has been a well-known phenomenon in acute phases and is directly connected with bowel necrosis followed by urgent laparotopy and/or patient death. Adjunctive balloon angioplasty with failed thrombolysis has been reported [4] but use has not popularized due to the fear of distal embolization. On the other hand, a well timed combined use of aspiration thrombectomy with angioplasty and stent could prove safe, effective and relatively longer term solution considering risk factor control remains optimum.Regarding our patient; with more than a day of symptom history, we thought it was too late for effective thrombolysis. And although the proximal site of the SMA and major branches was found to be occluded in our patient, signs of bowel necrosis on abdominal CT or X-Ray (for e.g. bowel wall edema or pneumatosis intestinalis) had not yet developed. This led the team decision towards relatively