Accelerated 2-D Real-Time Refraction-Corrected Transcranial Ultrasound Imaging

Mozaffarzadeh, Moein; Verschuur, Eric; Verweij, Martin D.; Jong, Nico de; Renaud, Guillaume

doi:10.1109/tuffc.2022.3189600

Cited by 12 publications

(9 citation statements)

References 89 publications

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“…It provides an optimal phase aberration correction everywhere in image as the true location and geometry of the aberrator is used to correct the phase aberration (see panel d in Figures 5, 7 and 8). In a previous publication [34], our group demonstrated that the GB method has the potential to enable real-time transcranial imaging (>10 frames/s) without injection of a contrast agent, and its performance is not affected by the heterogeneity (speckle) of the brain tissue; it only requires estimating the position and geometry of the bone layer, as shown in our previous publications [31][32][33]44]. The GB method is not limited to a maximum bone thickness as long as the attenuation caused by a thick bone layer allows detection of echo signals with sufficient signal-to-noise ratio.…”

Section: Advantages and Limitations Of The Geometry-based Phase Aberr...mentioning

confidence: 93%

“…We extensively described and evaluated the ARC-GB approach in Ref. [34]. In summary, it consists of 4 steps:…”

Section: Accelerated Refraction-corrected Geometry-based Phase Aberra...mentioning

confidence: 99%

“…To address this issue, a resource-efficient and accelerated ray-tracing approach was proposed in Ref. [34]. With implementation on a graphics processing unit (GPU), real-time GB aberration correction TUI became feasible and was named accelerated refraction-corrected (ARC) image reconstruction.…”

Section: Introductionmentioning

confidence: 99%

“…[28,29], a focused wave was used in transmission and a CT scan was used to obtain the geometry and sound speed of the skull. Our method estimates the position, geometry, and sound speed of the bone layer with ultrasound (no need for a CT or MRI scan) and using one probe [31] and enables real-time imaging [34].…”

Section: Introductionmentioning

confidence: 99%

“…Our method estimates the position, geometry, and sound speed of the bone layer with ultrasound (no need for a CT or MRI scan) and using one probe [31] and enables real-time imaging [34].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of Phase-Screen and Geometry-Based Phase Aberration Correction Techniques for Real-Time Transcranial Ultrasound Imaging

et al. 2022

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While transcranial ultrasound imaging is a promising diagnostic modality, it is still hindered due to phase aberration and multiple scattering caused by the skull. In this paper, we compare near-field phase-screen modeling (PS) to a geometry-based phase aberration correction technique (GB) when an ultrafast imaging sequence (five plane waves tilted from −15 to +15 degrees in the cutaneous tissue layer) is used for data acquisition. With simulation data, the aberration profile (AP) of two aberrator models (flat and realistic temporal bone) was estimated in five isoplanatic patches, while the wave-speed of the brain tissue surrounding the point targets was either modeled homogeneously (ideal) or slightly heterogeneously to generate speckle (for mimicking a more realistic brain tissue). For the experiment, a phased array P4-1 transducer was used to image a wire phantom; a 4.2-mm-thick bone-mimicking plate was placed in front of the probe. The AP of the plate was estimated in three isoplanatic patches. The numerical results indicate that, while all the scatterers are detectable in the image reconstructed by the GB method, many scatterers are not detected with the PS method when the dataset used for AP estimation is generated with a realistic bone model and heterogeneous brain tissue. The experimental results show that the GB method increases the signal-to-clutter ratio (SCR) by 7.5 dB and 6.5 dB compared to the PS and conventional reconstruction methods, respectively. The GB method reduces the axial/lateral localization error by 1.97/0.66 mm and 2.08/0.7 mm compared to the PS method and conventional reconstruction, respectively. The lateral spatial resolution (full-width-half-maximum) is also improved by 0.1 mm and 1.06 mm compared to the PS method and conventional reconstruction, respectively. Our comparison study suggests that GB aberration correction outperforms the PS method when an ultrafast multi-angle plane wave sequence is used for transcranial imaging with a single transducer.

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Section: Advantages and Limitations Of The Geometry-based Phase Aberr...mentioning

confidence: 93%

“…We extensively described and evaluated the ARC-GB approach in Ref. [34]. In summary, it consists of 4 steps:…”

Section: Accelerated Refraction-corrected Geometry-based Phase Aberra...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Our method estimates the position, geometry, and sound speed of the bone layer with ultrasound (no need for a CT or MRI scan) and using one probe [31] and enables real-time imaging [34].…”

Section: Introductionmentioning

confidence: 99%

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