The modern human society has seen the drastic impact of modern technologies and it is an undeniable fact that these new tools have significantly affected all facets of human interaction and have tremendously impacted human activities, either by causing mild alteration in the nature and structure of the contemporary world, or directly revolutionizing all the sections and sectors of human endeavors. In fact, one area the effects of technologies have been felt is the economy and the commercial sector. Technologies have continued impact and improve businesses across the world, and commercial activities have drifted towards the power and whims of the contemporary technological realities. Hence, many big businesses are adjusting their operations to utilise these new tools for productivity and profitability; affording them enormous competitive advantages. However, studies have showed that SMEs cannot afford expensive technologies or lack the financial wherewithal to adopt technological innovations. Worse still, SMEs in the developing nations contend with several challenges, and it has been determined that more than 80% of SMEs collapse or die during their first three years. The informal sector in every nation is key to the survival of every country, and if struggling nations continue to experience high business mortality in the informal sector, then the economy of the developing countries will continue to nosedive. Therefore, this work recognizes the transformative power of artificial intelligence and its potentials to improve SMEs. Therefore, this work seeks to examine how the developing nations can utilise AIs for more productivity, performance, engagement, business optimization and profitability amidst stiff challenges and the overwhelming influences of big businesses and multinationals.