Accelerometer-determined moderate intensity lifestyle activity and cardiometabolic health

Camhi, Sarah M.; Sisson, Susan B.; Johnson, William D.; Katzmarzyk, Peter T.; Tudor–Locke, Catrine

doi:10.1016/j.ypmed.2011.01.030

Cited by 77 publications

(68 citation statements)

References 16 publications

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“…In this respect, we were referred to a study by Camhi et al, 272 which is described below. This conversation also highlighted the Yates et al study, 267 discussed earlier.…”

Section: Economic Analysismentioning

confidence: 99%

“…The Camhi et al 272 study was cross-sectional, based on the US NHANES survey (National Health and Nutrition Examination Survey). This study 272 assessed the relationship between activity (steps per day) and cardiometabolic risk factors, including cholesterol.…”

Section: Description Of Key Studiesmentioning

confidence: 99%

“…This study 272 assessed the relationship between activity (steps per day) and cardiometabolic risk factors, including cholesterol. Data for 1371 adults were analysed and significant changes were observed in triglycerides, HDL cholesterol and waist circumference for each 1000 additional steps achieved, but does not report BMI changes or BP.…”

Section: Description Of Key Studiesmentioning

confidence: 99%

“…Data for 1371 adults were analysed and significant changes were observed in triglycerides, HDL cholesterol and waist circumference for each 1000 additional steps achieved, but does not report BMI changes or BP. The study 272 reported results as an OR of 0.91 (95% CI 0.81 to 0.96) of having HDL cholesterol above the cut-off point of 1.03 mmol/l (men) or 1.2 mmol/l (women).…”

Section: Description Of Key Studiesmentioning

confidence: 99%

“…For the purpose of parameterising the model, this study 272 was not preferred over the evidence from the Bravata et al study 269 because this is only a single study and is cross-sectional, whereas the Bravata et al study 269 is a meta-analysis of intervention studies.…”

Section: Description Of Key Studiesmentioning

confidence: 99%

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Screening for glucose intolerance and development of a lifestyle education programme for prevention of type 2 diabetes in a population with intellectual disabilities: the STOP Diabetes research project

Dunkley

Tyrer

Spong

et al. 2017

Programme Grants Appl Res

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BackgroundThe prevalence of type 2 diabetes mellitus (T2DM) and of cardiovascular disease (CVD) is believed to be higher among people with intellectual disability (ID) than in the general population. However, research on prevalence and prevention in this population is limited.ObjectivesThe objectives of this programme of work were to establish a programme of research that would significantly enhance the knowledge and understanding of impaired glucose regulation (IGR) and T2DM in people with ID; to test strategies for the early identification of IGR and T2DM in people with ID; and to develop a lifestyle education programme and educator training protocol to promote behaviour change in a population with ID and IGR (or at a high risk of T2DM/CVD).SettingLeicestershire, UK.ParticipantsAdults with ID were recruited from community settings, including residential homes and family homes. Adults with mild to moderate ID who had an elevated body mass index (BMI) of ≥ 25 kg/m2and/or IGR were invited to take part in the education programme.Main outcome measuresThe primary outcome of the screening programme was the prevalence of screen-detected T2DM and IGR. The uptake, feasibility and acceptability of the intervention were assessed.Data sourcesParticipants were recruited from general practices, specialist ID services and clinics, and through direct contact.ResultsA total of 930 people with ID were recruited to the screening programme: 58% were male, 80% were white and 68% were overweight or obese. The mean age of participants was 43.3 years (standard deviation 14.2 years). Bloods were obtained for 675 participants (73%). The prevalence of previously undiagnosed T2DM was 1.3% [95% confidence interval (CI) 0.5% to 2%] and of IGR was 5% (95% CI 4% to 7%). Abnormal IGR was more common in those of non-white ethnicity; those with a first-degree family history of diabetes; those with increasing weight, waist circumference, BMI, diastolic blood pressure or triglycerides; and those with lower high-density lipoprotein cholesterol. We developed a lifestyle educational programme for people with ID, informed by findings from qualitative stakeholder interviews (health-care professionals,n = 14; people with ID,n = 7) and evidence reviews. Subsequently, 11 people with ID (and carers) participated in pilot education sessions (two groups) and five people attended education for the feasibility stage (one group). We found that it was feasible to collect primary outcome measures on physical activity and sedentary behaviour using wrist-worn accelerometers. We found that the programme was relatively costly, meaning that large changes in activity or diet (or a reduction in programme costs) would be necessary for the programme to be cost-effective. We also developed a quality development process for assessing intervention fidelity.LimitationsWe were able to screen only around 30% of the population and involved only a small number in the piloting and feasibility work.ConclusionsThe results from this programme of work have significantly enhanced the existing knowledge and understanding of T2DM and IGR in people with ID. We have developed a lifestyle education programme and educator training protocol to promote behaviour change in this population.Future workFurther work is needed to evaluate the STOP Diabetes intervention to identify cost-effective strategies for its implementation.Trial registrationClinicalTrials.gov NCT02513277.FundingThe National Institute for Health Research Programme Grants for Applied Research programme and will be published in full inHealth Research Programme Grants for Applied Research; Vol. 5, No. 11. See the NIHR Journals Library website for further project information.

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“…In this respect, we were referred to a study by Camhi et al, 272 which is described below. This conversation also highlighted the Yates et al study, 267 discussed earlier.…”

Section: Economic Analysismentioning

confidence: 99%

Section: Description Of Key Studiesmentioning

confidence: 99%

Section: Description Of Key Studiesmentioning

confidence: 99%

Section: Description Of Key Studiesmentioning

confidence: 99%

Section: Description Of Key Studiesmentioning

confidence: 99%

See 3 more Smart Citations

Screening for glucose intolerance and development of a lifestyle education programme for prevention of type 2 diabetes in a population with intellectual disabilities: the STOP Diabetes research project

Dunkley

Tyrer

Spong

et al. 2017

Programme Grants Appl Res

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Associations between accelerometer-derived physical activity and regional adiposity in young men and women

Smith

Storti

Arena

et al. 2013

Obesity

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Objective Empirical evidence supports an inverse relationship between physical activity (PA) and adiposity, but studies using detailed measures of both are scarce. We described the relationship between regional adiposity and accelerometer-derived PA in men and women. Design and Methods Cross-sectional analysis included 253 participants from a weight loss study limited to ages 20–45 years and BMI 25–39.9 kg/m2. PA data were collected with accelerometers and expressed as total accelerometer counts and average amount of time per day accumulated in different intensity levels (sedentary, light-, and moderate- to vigorous- intensity PA (MVPA)). Accumulation of time spent above 100 counts was expressed as total active time. Computed tomography (CT) was used to measure abdominal and adipose tissue (AT). Multivariate linear regression analyses were used to assess the relationship between regional adiposity (dependent variable) and the various PA levels (independent variable), and were executed separately for men and women, adjusting for wear time, age, race, education, and BMI. Results Among males light activity was inversely associated with total AT (β=−0.19; p=0.02) as well as visceral AT (VAT) (β=−0.30; p=0.03). Among females sedentary time was positively associated with VAT (β=0.11; p=0.04) and total active time was inversely associated with VAT (β=−0.12; p=0.04). Conclusions Findings from this study suggest that PA intensity level may influence regional adiposity differently in men and women. Additional research is needed in larger samples to clarify the difference in these associations by sex, create recommendations for the frequency, duration and intensity of PA needed to target fat deposits, and determine if these recommendations should differ by sex.

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Replacing sedentary time with light activity was associated with less adiposity across several depots in African ancestry men

Marron

Cvejkus

Acevedo-Fontanez

et al. 2022

Obesity

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ObjectiveThe aim of this study was to determine whether displacement of sedentary time with activity was cross‐sectionally associated with less adiposity among Black Caribbean men in the Tobago Health Study.MethodsObjectively assessed activity was categorized as sedentary (< 1.5 metabolic equivalents; METs), light (≥ 1.5 to < 3.0 METs), or moderate‐to‐vigorous (≥ 3.0 METs) using the SenseWear Pro armband. Computed tomography scans of the chest, abdomen, liver, and thigh were used to assess subcutaneous and ectopic adipose tissue. The isotemporal substitution framework paired with linear regression was used to examine associations between activity and adiposity adjusting for age, height, total awake time, and multiple comparisons.ResultsOn average, participants (n = 271) were 63 years old with 11.2 h/d of sedentary behavior, 4.5 h/d of light activity, and 54 min/d of moderate‐to‐vigorous activity. Replacing sedentary time with light activity was cross‐sectionally associated with lower volume and higher density of abdominal and thigh subcutaneous adiposity, visceral adiposity, abdominal and thigh intermuscular adiposity, and pericardial adiposity and higher liver attenuation (p values ≤ 0.0001).ConclusionsDisplacement of sedentary time with light activity was associated with less adiposity among this Black Caribbean cohort. Interventions focused on increasing light activity may be easier to maintain than higher intensity interventions and thus may be more successful at reducing adiposity.

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Accelerometer-determined moderate intensity lifestyle activity and cardiometabolic health

Cited by 77 publications

References 16 publications

Screening for glucose intolerance and development of a lifestyle education programme for prevention of type 2 diabetes in a population with intellectual disabilities: the STOP Diabetes research project

Screening for glucose intolerance and development of a lifestyle education programme for prevention of type 2 diabetes in a population with intellectual disabilities: the STOP Diabetes research project

Associations between accelerometer-derived physical activity and regional adiposity in young men and women

Replacing sedentary time with light activity was associated with less adiposity across several depots in African ancestry men

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