Acceptance of herbal medicines in andrology

George, Annie; Liske, Eckehard

doi:10.1016/b978-0-12-815565-3.00009-6

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…Fenugreek ( Trigonella foenum-graecum ) seeds have been considered to work well in cases of ED, male libido, sexual function, androgenic hormone level and can significantly decrease the total score for aging male syndrome (AMS). Roots of the age-old Ayurvedic herb “Ashwagandha” ( Withania somnifera ) is used to treat patients with low levels of testosterone and LH, semen volume, sperm count, sperm motility [ 295 , 296 ]. Other Indian traditional herbs used in Ayurveda and Unani systems of medicine, including Asparagus racemosus , Mucuna pruriens , Tinospora cardifolia , Orchis latifolia , may also help in combating aging, male reproductive tract disorder and helps in increasing quantity of semen as well as work as aphrodisiacs [ 297 ].…”

Section: Future Perspectivesmentioning

confidence: 99%

“…Other Indian traditional herbs used in Ayurveda and Unani systems of medicine, including Asparagus racemosus , Mucuna pruriens , Tinospora cardifolia , Orchis latifolia , may also help in combating aging, male reproductive tract disorder and helps in increasing quantity of semen as well as work as aphrodisiacs [ 297 ]. Herbs, such as “Tongkat Ali” ( Eurycoma longifolia ), are used for managing hypogonadism in Southeast Asian countries [ 295 ]. Studies on Japanese “Kampo” medicine, Korean herbal formulation “Ojayeonjonghwan” or KH-204, and Chinese herbal medicine saikokaryukotsuboreito (SKRBT) have reported their potential efficacy in managing hypogonadism [ 298 , 299 , 300 ].…”

Section: Future Perspectivesmentioning

confidence: 99%

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Environmental Factors-Induced Oxidative Stress: Hormonal and Molecular Pathway Disruptions in Hypogonadism and Erectile Dysfunction

et al. 2021

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Hypogonadism is an endocrine disorder characterized by inadequate serum testosterone production by the Leydig cells of the testis. It is triggered by alterations in the hypothalamic–pituitary–gonadal axis. Erectile dysfunction (ED) is another common disorder in men that involves an alteration in erectile response–organic, relational, or psychological. The incidence of hypogonadism and ED is common in men aged over 40 years. Hypogonadism (including late-onset hypogonadism) and ED may be linked to several environmental factors-induced oxidative stresses. The factors mainly include exposure to pesticides, radiation, air pollution, heavy metals and other endocrine-disrupting chemicals. These environmental risk factors may induce oxidative stress and lead to hormonal dysfunctions. To better understand the subject, the study used many keywords, including “hypogonadism”, “late-onset hypogonadism”, “testosterone”, “erectile dysfunction”, “reactive oxygen species”, “oxidative stress”, and “environmental pollution” in major online databases, such as SCOPUS and PUBMED to extract relevant scientific information. Based on these parameters, this review summarizes a comprehensive insight into the important environmental issues that may have a direct or indirect association with hypogonadism and ED in men. The study concludes that environmental factors-induced oxidative stress may cause infertility in men. The hypothesis and outcomes were reviewed critically, and the mechanistic approaches are applied through oxidant-sensitive pathways. This study also provides reccomendations on future therapeutic interventions and protective measures against such adverse environmental factors-induced hypogonadism and ED.

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Section: Future Perspectivesmentioning

confidence: 99%