Acceptance of human papillomavirus vaccine among boys in Asia: A narrative review

Abstract

Human papillomavirus (HPV) is a prevalent sexually transmitted infection globally, linked to genital warts and various cancers. The burden of HPV-related diseases in males is rising significantly. We reviewed studies published until September 2024 from databases like PubMed, Embase®, and Web of Science, summarizing HPV vaccination acceptance among boys and parents in Asia and exploring influencing factors. Acceptance rates for HPV vaccination among boys ranged from 48.4% to 69.9%, while parental acceptance varied from 10.0% to 91.0%. Recent years have shown a positive trend in acceptance, influenced by perceived risk and benefits, barriers, sociodemographic characteristics, knowledge and awareness of HPV and its vaccine, and social support factors. Targeted educational interventions are crucial for increasing awareness of male-associated HPV diseases and for dispelling misconceptions. The future implementation of gender-neutral vaccination policies may facilitate broader acceptance. Future studies should focus on developing interventions to promote pan-gender HPV vaccination.