An outbreak of coronavirus disease 2019 , now known to be caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that began in China in December 2019, has since spread rapidly throughout the world. 1 There are several reports of hemodialysis patients with COVID-19. [2][3][4] Hemodialysis patients appear to be a population at high risk for severe COVID-19, because factors identified as risk factors for severe COVID-19 are often present in these patients: old age, hypertension, cardiovascular comorbidity, and diabetes mellitus. In addition, these patients also show impaired antiviral immune responses, because of the impaired kidney function. On the other hand, hemodialysis patients may not be at a higher risk for more severe COVID-19 in other respects: They are also aware of their vulnerable condition, they know that they should seek medical advice immediately when they have fever or other complaints, and they have an immunosuppressed state which may attenuate the hyperinflammatory response observed in the stage of severe COVID-19. The usual clinical course of hemodialysis patients with COVID-19 is not yet clear. We examined 5 hemodialysis patients with COVID-19 at our hospital and report, herein, the prolonged persistence of a positive result of the PCR test for SARS-CoV2 in hemodialysis patients.