Misuse of opioid analgesics and other psychoactive medicines is a serious and increasing problem in Australia. Measures are being taken to try and prevent this progressing to a public health crisis like the opioid overdose epidemic seen in the USA. One measure is real-time prescription monitoring. This provides real-time information about the patient's supply of psychoactive medicines which have a high risk of being misused. Having identified a patient at risk, many factors may delay appropriate management or result in the patient being discharged from care. These factors include subconscious negative stereotyping, a focus on preventing 'doctor shoppers' diverting psychoactive medicines, and a fear of sanction by regulators. The Medical Board of Australia provides guidance about good practice. Patients should be treated with respect, free from bias and discrimination, and without prejudicing care because of the belief that their behaviour has contributed to their problems. seeking psychoactive medicines for their intoxicating effect or for trafficking. 2 Trust is basic to the doctor-patient relationship. When this is exploited by a drug-seeking person it may cause negative feelings and indiscriminate refusal to continue treatment for other patients assumed to be fraudulently seeking prescriptions. The focus on preventing 'doctor shoppers' may influence this attitude but, like any other medical condition, patients with multiple providers will benefit from a patientcentred approach. Escalating opioid prescribing There was a 15-fold increase in the supply of prescription opioids between 1992 and 2012. 3 During this time several new, potent opioids and many new formulations were marketed in Australia. Approximately three million Australians now use opioids each year. About 2.5 million report lifetime non-medical use of pharmaceutical drugs. In 2016 more than 700,000 Australians used opioid analgesics non-medically to achieve a drug effect. 4 Every day there are nearly 150 hospitalisations, 14 emergency department presentations and three deaths involving opioids. 5 Increasing numbers of people are being treated in alcohol and drug clinics or being prescribed medicines to treat pharmaceutical opioid dependence. Opioids and benzodiazepines are commonly involved in overdose deaths. Non-medical use of opioid