“…33,34 On the other hand, arguments against such a causal association are: (i) PD is asymptomatic in the vast majority of individuals, [35][36][37] (ii) there is no significant difference in the prevalence of PD between the pancreatitis and non-pancreatitis patient groups in a large series of patients undergoing ERCP, 38 and (iii) the response to minor papilla sphincterotomy is variable and suboptimal in the majority of patients presenting with RAP and CP. 39,40 The prevalence of PD in RAP varies across various studies (Table 6). 25,[35][36][37][41][42][43] A recent community-based study from Japan included 504 subjects from the general population, and 46 patients with pancreatitis (8 AP, 23 CP and 15 RAP).…”