2024
DOI: 10.3390/biom14101280
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Accumbal Dopamine Responses Are Distinct between Female Rats with Active and Passive Coping Strategies

Vsevolod V. Nemets,
Ekaterina P. Vinogradova,
Vladislav Zavialov
et al.

Abstract: There is a gap in existing knowledge of stress-triggered neurochemical and behavioral adaptations in females. This study was designed to explore the short-term consequences of a single social defeat (SD) on accumbal dopamine (DA) dynamics and related behaviors in female Wistar rats. During the SD procedure, rats demonstrated different stress-handling strategies, which were defined as active and passive coping. The “active” subjects expressed a significantly higher level of activity directed toward handling str… Show more

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