Accumulation of Functional Block Telomers on Metal Surfaces

Abstract

A disulfide-group-carrying novel iniferter (a compound which pursues initiation, chain transfer, and termination) (Cys-BDC) was prepared by coupling N,N-diethyldithiocarbamoylmethylbenzoic acid succinimidyl ester with cystamine dihydrochloride. Block copolymerization of methacrylic acid (MA) and 2-methacryloyloxyethyl D-glucopyranoside (MEGlc) was performed by successive UV-irradiation in the presence of the iniferter and N,N,N′,N′-tetraethylthiuram disulfide. The block telomer formed a selfassembled monolayer (SAM) on a gold electrode and vacuum-evaporated gold thin film, as confirmed by cyclic voltammetry and infrared reflection-absorption spectroscopy (IRRAS), respectively. The pHresponsiveness of the MA telomer block on the gold surface and silver colloid was confirmed by contact angle and ζ-potential measurements, respectively. Recognition of glucose residues in the MEGlc block by a lectin (Concanavalin A) was followed on the gold surface and silver colloid by IRRAS and turbidity measurements, respectively. Our results strongly support the usefulness of the iniferter for the preparation of various block-telomer-carrying SAMs with biorelated functions.

Kinetic study on the binding of lectin to mannose residues in a polymer brush

“…The gold surface was modified with the well-defined polymercarrying disulfide, which had been prepared in the solution phase using the ATRP method beforehand ("grafting-to" method). Previously, it was not possible to prepare a polymer brush using a surface-confined photo-iniferter (iniferter; a compound with the abilities of initiation, transfer, and termination) in the presence of vinyl monomer [54], because the iniferter SAM was mostly decomposed or forced to migrate from the gold surface during the UV-irradiation.…”

Interaction of wheat germ agglutinin with an N-acetylglucosamine-carrying telomer brush accumulated on a colloidal gold monolayer

“…An azo-type radical initiator with dioctadecyl groups at both ends (DODA-501, Scheme 1(A)) [45][46][47][48] and the disulfidecarrying photo-iniferter (Cys-BDC, Scheme 1(B)) [23] were prepared as described earlier. A polymerizable phospholipid (bis(trans, trans-2,4-dioctadecadienoyl)phosphatidyl choline, DDPC) and 3-aminopropyl triethoxysilane (APTS) were purchased from Japan Fat & Oil Co., Tokyo, Japan and ShinEtsu Chemicals, Tokyo, Japan, respectively.…”

Wrapping of Single‐Walled Carbon Nanotubes with A‐B‐A Block Telomers

“…[3] Many kinds of block copolymers have been prepared by ''living'' polymerization. [4] On the other hand, macroinitiators, which are polymeric compounds with an ability to initiate polymerization reactions, have been paid keen attention to enable easy preparation of functional block copolymers.…”