Accumulation of zinc, nickel, lead and cadmium in some organs of rabbits after dietary nickel and zinc inclusion

Kalafová, Anna; Kováčik, Jaroslav; Capcarová, Marcela; Kolesárová, Adriana; Lukáč, Norbert; Stawarz, Robert; Formicki, Grzegorz; Łaciak, T.

doi:10.1080/10934529.2012.672073

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…According to our research, the liver contained higher values of all the examined elements in comparison with the meat. These results are consistent with the studies of Cygan-Szczegielniak et al [ 32 ] and Kalafova et al [ 33 ]. A liver is the primary target organ for heavy metals principally because it serves as a store for metals, redistribution, and detoxification.…”

Section: Discussionsupporting

confidence: 94%

Effect of a Diet Supplemented with Nettle (Urtica dioica L.) or Fenugreek (Trigonella Foenum-Graecum L.) on the Content of Selected Heavy Metals in Liver and Rabbit Meat

Pałka

Drąg‐Kozak

Migdał

et al. 2022

Animals

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The literature on herbal additives for rabbit feed offers little information on the use of nettle and fenugreek. Both of these herbs are valuable sources of vitamins and minerals. These herbs affect the growth, health, and meat quality of rabbits. They regulate the digestive system, stimulate the appetite, have a positive effect on the functioning of the immune system, and exhibit antibacterial activity. The purpose of the present study was to determine the effect of nettle (Urtica dioica L.) leaves or fenugreek (Trigonella foenum-graecum L.) seeds in the feed on the content of selected heavy metals in the liver and meat of the rabbit. The rabbits were divided into three groups: group C (n = 20; 10 ♂ and 10 ♀) was fed ad libitum with a complete feed, N group (n = 20; 10 ♂ and 10 ♀) was fed a complete mixture with 1% added nettle, and group F (n = 20; 10 ♂ and 10 ♀) was fed with a complete mixture with 1% added fenugreek. The experiment lasted 7 weeks (from the 35th to the 84th day of the rabbits’ lives). All the rabbits were slaughtered on the 84th day of age, with a body weight of about 2.6 kg. The concentration of heavy metals (Zn, Cu, Ni, Mn, Fe, Pb, Cd) was determined by the atomic absorption spectrometry (AAS). The additives to the feed significantly affected the content of elements in both the liver and the meat of rabbits (p < 0.05). The highest level of the heavy metals, regardless of the used diet, was recorded in the liver (p < 0.05). The meat (m. longissimus lumborum) and the liver of rabbits fed with herbal fodder contained less tested metals than in animals fed with fodder without additives (p < 0.05). Moreover, more essential metals were found in the liver of rabbits fed with fenugreek than rabbits fed with nettle. In the meat and liver of rabbits, the permissible content of cadmium and lead was not exceeded. Additionally, male livers had a significantly higher content of copper and manganese compared to female livers (p < 0.05). It is important to study the content of heavy metals in the used animal herbal feed additives and their interaction with each other, as they affect the distribution of elements in tissues and organs.

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Section: Discussionsupporting

confidence: 94%

Effect of a Diet Supplemented with Nettle (Urtica dioica L.) or Fenugreek (Trigonella Foenum-Graecum L.) on the Content of Selected Heavy Metals in Liver and Rabbit Meat

Pałka

Drąg‐Kozak

Migdał

et al. 2022

Animals

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“…Kalafová et al (2012b) investigated the effect of dietary Ni and a combination of Ni and Zn on the accumulation of Pb, Cd, Ni and Zn in muscles, liver and kidneys of adult female rabbits. The inclusion of Ni (175 or 350 mg NiCl 2 /kg) and Zn to the diet for rabbits for 90 days had no effect on the concentration of Ni and Zn in liver, kidney and muscle (musculus biceps femoris and musculus longissimus dorsi).…”

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Scientific Opinion on the risks to animal and public health and the environment related to the presence of nickel in feed

Publication¹

2015

EFS2

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Following a request from the European Commission, the risks to animal and human health and the environment related to the presence of nickel (Ni) in feed were assessed by the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel). The presence of Ni in feed can arise from both natural and anthropogenic sources. Additionally, certain feed materials contain metallic Ni, since it is used as a catalyst in their production. Based on the differences observed between the Ni exposure levels estimated for different animal species and identified no observed adverse effect levels (NOAELs) and lowest observed adverse effect levels (LOAELs), the CONTAM Panel concluded that any adverse impact of Ni via feed to cattle, pigs, rabbits, ducks, fish, dogs, chickens, horses, sheep, goats and cats is unlikely. Concerning the assessment of human health risks from the presence of Ni in food of animal origin, the CONTAM Panel concluded that in the average population the current levels of chronic exposure to Ni, considering only foods of animal origin, might be of potential concern in the young population, in particular in 'Toddlers'. In the highly exposed population (95th percentile), the concern also extends to the age class 'Other children'. Regarding acute dietary exposure, the CONTAM Panel concluded that Ni-sensitized individuals are also at risk of developing eczematous flare-up skin reactions through the consumption of food of animal origin. The contribution of food of animal origin to human dietary exposure to Ni should therefore not be underestimated, particularly in age classes with high dietary exposure to Ni. Release to the environment from manure, resulting from its presence in animal feed, is not a major contributor of Ni deposited onto agricultural soils or to the environment. SUMMARYFollowing a request from the European Commission, the risks to animal and human health and the environment related to the presence of nickel (Ni) in feed were assessed by the EFSA Panel on Contaminants in the Food Chain (CONTAM Panel).Ni is a metal that occurs in a number of different soluble and particulate forms, which are ubiquitously found in the environment both from natural occurrence and from anthropogenic activity. Animal feed contains Ni, particularly in the divalent form, its most stable oxidation state. Additionally certain vegetable oils can contain traces of metallic Ni, since it is used as a catalyst in their hydrogenation.Following a call for data, two European countries, submitted 1 813 results on Ni concentrations in feed of which 1 794 were from one country. All results were reported as total Ni, with no differentiation between Ni species. Feed related exposure to Ni was estimated by applying two different scenarios, namely (i) exposures based on Ni concentrations in compound feed and forages and (ii) exposures derived from Ni in feed materials including hydrogenated vegetable oils. For compound feed, 317 results were provided, though the livestock species for which these feeds had been manufactured were not gi...

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Environmental contaminants and their influence on health and female reproduction

Sirotkin¹,

Kolesárová²

2022

Environmental Contaminants and Medicinal Plants Action on Female Reproduction

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Accumulation of zinc, nickel, lead and cadmium in some organs of rabbits after dietary nickel and zinc inclusion

Cited by 4 publications

References 31 publications

Effect of a Diet Supplemented with Nettle (Urtica dioica L.) or Fenugreek (Trigonella Foenum-Graecum L.) on the Content of Selected Heavy Metals in Liver and Rabbit Meat

Effect of a Diet Supplemented with Nettle (Urtica dioica L.) or Fenugreek (Trigonella Foenum-Graecum L.) on the Content of Selected Heavy Metals in Liver and Rabbit Meat

Scientific Opinion on the risks to animal and public health and the environment related to the presence of nickel in feed

Environmental contaminants and their influence on health and female reproduction

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