Accuracy and precision of the Cholestech LDX System in monitoring blood lipid levels

Santee, Jennifer

doi:10.1093/ajhp/59.18.1774

Cited by 28 publications

(27 citation statements)

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“…Fasting lipid and glucose concentrations were determined using Cholestech Analyzers (Cholestech LDX System®, Hayward, CA) and a single finger-stick blood sample. Because the accuracy of this instrument is dependent upon technique, 27 the same trained members of our research team performed the cholesterol and glucose analyses at both assessment time points.…”

Section: Methodsmentioning

confidence: 99%

Physical Activity for Campus Employees: A University Worksite Wellness Program

Butler

Clark

Burlis

et al. 2015

Journal of Physical Activity and Health

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Background Workplaces provide ideal environments for wellness programming. The purpose of this study was to explore exercise self-efficacy among university employees and the effects of a worksite wellness program on physical activity, cardiorespiratory fitness, and CVD risk factors. Methods Participants included 121 university employees (85% female). The worksite wellness program included cardiovascular health assessments, personal health reports, 8 weeks of pedometer-based walking and tracking activities, and weekly wellness sessions. Daily step count was assessed at baseline, week 4, and week 8. Exercise self-efficacy and CVD risk factors were evaluated at baseline and follow-up. Results Daily step count increased from 6566 ± 258 (LSM ± SE) at baseline to 8605 ± 356 at week 4 and 9107 ± 388 at week 8 (P < .0001). Steps increased among normal weight, overweight, and obese sub-groups. Exercise self-efficacy correlated with baseline steps (P < .05). Small improvements were observed in cardiorespiratory fitness, BMI, blood pressure, blood glucose, total cholesterol, and triglycerides (all P < .01). Conclusions A worksite wellness program was effective for increasing physical activity, cardiorespiratory fitness, and CVD risk factors among university employees. Exercise barriers and outcome expectations were identified and have implications for future worksite wellness programming.

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Section: Methodsmentioning

confidence: 99%

Physical Activity for Campus Employees: A University Worksite Wellness Program

Butler

Clark

Burlis

et al. 2015

Journal of Physical Activity and Health

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“…[12, 13] Non-fasting total cholesterol and HDL-C concentrations were measured from capillary blood using an LDX lipid analyzer. [14, 15] Because the goal of the study was to demonstrate weight loss effectiveness of the adapted DPP intervention while minimizing the measurement burden on patients and clinicians, the RAPID Study protocol did not replicate DPP clinical trial protocols that also included fasting or timed glucose tolerance testing.…”

Section: Methodsmentioning

confidence: 99%

Rationale, design, and baseline characteristics of a community-based comparative effectiveness trial to prevent type 2 diabetes in economically disadvantaged adults: The RAPID Study

Ackermann

Finch

Schmidt

et al. 2014

Contemporary Clinical Trials

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Reaching out And Preventing Increases in Diabetes (RAPID) is a community-based randomized trial evaluating the comparative costs and effectiveness of a group-based adaption of the DPP lifestyle intervention developed and implemented in partnership with the YMCA. RAPID enrolled adult primary care patients, with BMI 24 kg/m2 or higher and abnormal glucose metabolism (HbA1c 5.7-6.9% or fasting plasma glucose 100-125 mg/dL). 509 participants were enrolled and randomized to one of two groups: standard clinical advice plus free-of-charge access to a group-based adaption of the DPP offered by the Y, versus standard clinical advice alone. Key outcomes for future analysis will include differences in body weight and other cardiovascular risk factors over a 24-month intervention period. At baseline, RAPID participants had a mean (SD) age of 51 ± 12.1 years, weight of 225.1 ± 56.2 Ibs, and BMI of 36.9 ± 8.6 kg/m2. 70.7% were women, 57.2% were African American, 35.4% were non-Hispanic White, and 3.2% were Hispanic. Mean HbA1c was 6.05 ± 0.34%. Additionally, 55.4% of participants had a baseline systolic blood pressure of ≥130 mmHg, 33.1% had a total blood cholesterol exceeding 200 mg/dl, and 74% reported a household income of <$25,000. The RAPID Study successfully randomized a large cohort of participants with a wide distribution of age, body weight, and race who are at high risk for developing type 2 diabetes.

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“…We included all patients who were working at the moment of the screening and without physical limitations (NYHA Functional Class I). Cholesterol levels were measured in a fasting state by means of Cholestech LDX® System [13].…”

Section: Methodsmentioning

confidence: 99%