This study aims to 1) develop MachineLearning Ecosystem models to enhance grade point averages, and 2) predict grade point averages by modeling Machine Learning Ecosystem techniques, namely, Decision Trees (DT), Naï ve Bayes (NB), and a Neural Network (NN). Findings from an efficiency comparison of the three models of a Machine Learning Ecosystem in predicting grade point averages showed that DT achieved the highest accuracy of 100.00%. In contrast, NN achieved the second-highest accuracy of 85.83%, and NB achieved the lowest accuracy of 81.67%. For the F-Measure, the F-Measure with DT, NN, and NB was 100.00%, 76.59%, and 70.59%, respectively. Thus, DT was the most appropriate model for a Machine Learning Ecosystem to predict the students' GPA.