Accuracy of Capsule Colonoscopy and Computed Tomographic Colonography in Individuals With Positive Results From the Fecal Occult Blood Test

Rondonotti, Emanuele; Borghi, C.; Mandelli, G.; Radaelli, Franco; Paggi, Silvia; Amato, Arnaldo; Imperiali, G.; Terreni, Natalia; Lenoci, Nicoletta; Terruzzi, Vittorio; Baccarin, Alessandra; Martegani, Alberto; Spinzi, Giancarlo

doi:10.1016/j.cgh.2013.12.027

Cited by 75 publications

(77 citation statements)

References 13 publications

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“…All four cases of CRC were detected by the capsule. A recent study compared colon capsule endoscopy using the PillCam2 capsule to CT colonography to preselect individuals with positive fecal occult blood test to optical colonoscopy by identifying those with at least one polyp greater than 6 mm [8]. They found that both methods detect the polyps in 16 of 50 cases with high level of accuracy: sensitivity of the capsule was 88 %, specificity 88 %, and PLR of 3.75 and NLR of 0.06.…”

Section: Surveillancementioning

confidence: 94%

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Colon PillCam: Why Not Just Take a Pill?

Eliakim

Adler

2015

Dig Dis Sci

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This review article deals with the clinical value of capsule endoscopy for visualization of the colon. Since its introduction in 2006, the colon capsule endoscopy underwent major technological improvements. The improved performance of colon capsule endoscopy is reviewed based on three multicenter prospective studies. Screening patients for colonic adenomatous polyps is reasonable in patients who are unwilling to undergo conventional colonoscopy. Another prospective study proved that colon capsule endoscopy is effective in incomplete colonoscopy. Colon capsule endoscopy was shown to be superior to virtual colonography in the evaluation of patients with incomplete colonoscopy. Further improvements are expected in colon capsule endoscopy.

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Section: Surveillancementioning

confidence: 94%

“…They found that both methods detect the polyps in 16 of 50 cases with high level of accuracy: sensitivity of the capsule was 88 %, specificity 88 %, and PLR of 3.75 and NLR of 0.06. Most subjects preferred the capsule exam to the CT colonography [8].…”

Section: Surveillancementioning

confidence: 99%

Colon PillCam: Why Not Just Take a Pill?

Eliakim

Adler

2015

Dig Dis Sci

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“…This time and labour-intensiveness can significantly impact on everyday clinical activities. For instance, due to its patient acceptability, CCE-2 has been proposed as a possible "filter" or screening test for the selection of patients for conventional colonoscopy (39,41). Nevertheless, the amount of resources and manpower required for the provision of such service may place further strain on already-overstretched healthcare services.…”

Section: Limitations Faced By Ccementioning

confidence: 99%

Review: capsule colonoscopy—a concise clinical overview of current status

Yung¹,

Rondonotti²,

Koulaouzidis³

2016

Ann. Transl. Med.

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Abstract:The colon capsule endoscopy (CCE) was first introduced in 2007. Currently, the main clinical indications for CCE are completion of incomplete colonoscopy, polyp detection and investigation of inflammatory bowel disease (IBD). Although conventional colonoscopy is the gold standard in bowel cancer screening, incomplete colonoscopy remains a problem as lesions are missed. CCE compares favourably to computer tomography colonography (CTC) in adenoma detection and has therefore been proposed as a method for completing colonoscopy. However the data on CCE remains sparse and current evidence does not show its superiority over CTC or conventional colonoscopy in bowel cancer screening. CCE also seems to show good correlation with conventional colonoscopy when used to evaluate IBD, but there are not many published studies at present. Other significant limitations include the need for aggressive bowel preparation and the labour-intensiveness of CCE reading. Therefore, much further software and hardware development is required to enable CCE to fulfill its potential as a minimally-invasive and reliable method of colonoscopy.

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“…A few studies comparing it to virtual colonoscopy in patients with incomplete colonoscopy were published with good results (16,17).…”

Section: Colon Capsule Endoscopy (Cce)-currentmentioning

confidence: 99%

Where do I see minimally invasive endoscopy in 2020: clock is ticking

Eliakim

2017

Ann. Transl. Med.

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Since it was introduced 17 years ago, capsule endoscopy has become an important diagnostic tool for the small bowel. Three generations of the original small bowel capsule have been developed since (PillCam SB3, Medtronic, USA), and four competitors were introduced for the small bowel. A non-video patency capsule (Agile patency capsule, Medtronic, USA) was also developed, in order to confirm patency and thus avoid retention in the GI tract. Moreover, capsules viewing other organs of the body (esophagus, colon) as well as three different magnetic guided capsules that visualize the stomach as good as optical endoscopy (OE) have been developed. Over 2,000 articles looking at the efficacy of the small bowel capsule in different clinical situations were published since then.Studies are comparing capsule endoscopy versus other modalities in various indications, looking at preparations aiming to improve the diagnostic yield and at technical aspects. The present paper, describes the available capsules in the market and my biased future expectations.Keywords: Small bowel capsule endoscopy (SBCE); colon capsule endoscopy (CCE); magnetic capsule endoscopy (MCE); optical endoscopy (OE)

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Accuracy of Capsule Colonoscopy and Computed Tomographic Colonography in Individuals With Positive Results From the Fecal Occult Blood Test

Cited by 75 publications

References 13 publications

Colon PillCam: Why Not Just Take a Pill?

Colon PillCam: Why Not Just Take a Pill?

Review: capsule colonoscopy—a concise clinical overview of current status

Where do I see minimally invasive endoscopy in 2020: clock is ticking

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