Accuracy of Capsule Colonoscopy in Detecting Colorectal Polyps in a Screening Population

Abstract

In an average-risk screening population, technically adequate capsule colonoscopy identified individuals with 1 or more conventional adenomas 6 mm or larger with 88% sensitivity and 82% specificity. Capsule performance seems adequate for patients who cannot undergo colonoscopy or who had incomplete colonoscopies. Additional studies are needed to improve capsule detection of serrated lesions. Clinicaltrials.gov number: NCT01372878.

S3-Leitlinie – Kolorektales Karzinom

“…Als Vorsorge-Methode erreichte die Kapsel-Koloskopie ebenfalls gute Werte für Adenome ≥ 6 mm (Sens 81 %, Spez. 93 %), eines von vier Karzinomen wurde aber übersehen und es wurden 21 % der initial eingeschlossenen Patienten von der finalen Analyse ausgeschlossen [443]. Aufgrund dieser Limitationen ist die Kolonkapsel derzeit nicht als primäre Screening-Methode zu empfehlen.…”

Colon capsule endoscopy: toward the future

“…To date, five studies have been published on polyp detection by CCE-2 compared with conventional colonoscopy [27][28][29][30][31]. These studies highlighted the considerably high sensitivity and specificity of CCE-2.…”

Where do I see minimally invasive endoscopy in 2020: clock is ticking

“…There have been two multicenter studies comparing, head to head, 2 nd generation CCE to optical colonoscopy, latter being the "gold standard" (5,6), and also one big study comparing both modalities in average risk surveillance population (15). A few studies comparing it to virtual colonoscopy in patients with incomplete colonoscopy were published with good results (16,17).…”