2010
DOI: 10.1016/j.jcrc.2009.05.008
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Accuracy of clinical definitions of ventilator-associated pneumonia: Comparison with autopsy findings

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Cited by 171 publications
(114 citation statements)
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References 14 publications
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“…Despite VAP epidemiological impact, it has no valid and reliable definition and even the most widely used VAP criteria are neither sensitive nor specific (6) and lack accuracy and objectivity (7,12,13), with documented poor correlation between the clinical diagnosis of VAP and histologic examination (14). Clinical scores have been applied but none was consistent in accurately identifying VAP (15).…”
Section: Vap Definitionmentioning
confidence: 99%
“…Despite VAP epidemiological impact, it has no valid and reliable definition and even the most widely used VAP criteria are neither sensitive nor specific (6) and lack accuracy and objectivity (7,12,13), with documented poor correlation between the clinical diagnosis of VAP and histologic examination (14). Clinical scores have been applied but none was consistent in accurately identifying VAP (15).…”
Section: Vap Definitionmentioning
confidence: 99%
“…All existing definitions have many subjective components, and none has been shown to be more accurate than another. 20,21 All yield many false positives and false negatives relative to histological evaluation at autopsy. Rather than try to come up with a new VAP definition then, the working group suggested shifting the focus of surveillance away from pneumonia to complications of mechanical ventilation instead.…”
Section: Limitations Of Vap As a Quality Metric For Ventilated Patientsmentioning
confidence: 99%
“…47 Autopsy series also find that 40 -60% of subjects who meet clinical criteria for VAP do not have histological evidence of pneumonia. 21 VAP is therefore a questionable standard against which to measure the accuracy of VAE definitions.…”
Section: The Sensitivity Of Vae Definitions For Vap Is Lowmentioning
confidence: 99%
“…: loose defi nition, 9 rigorous defi nition, 9 the clinical pulmonary infection score (CPIS) . 6, 10,11 the Canadian Critical Care Trials Group (CCCTG) classifi cation (possible type), 12 the International Sepsis Forum Consensus defi nition (probable type), 13 the CDC criteria, 14 and the new VAE algorithm.…”
mentioning
confidence: 99%